Results 41 to 50 of about 391,207 (312)

Extended reality technology – a new component in industrial engineering and production systems

Российский технологический журнал, 2020
Extended (virtual, augmented and mixed) reality technology gets considered as a new universal component of production (industrial) engineering’s methodological basis, receiving the possibilities for wide use in both extensive and intensive development of
A. S. Zuev, M. A. Makushchenko, M. E. Ivanov, E. S. Merkulov   +3 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Improving Urgency-Based Backlog Sequencing of Jobs: An Assessment by Simulation

Machines, 2022
When order release is applied, jobs are withheld in a backlog from where they are released to meet certain performance targets. The decision that selects jobs for release is typically preceded by a sequencing decision.
Nuno O. Fernandes, Matthias Thürer, Mark Stevenson, Silvio Carmo-Silva   +3 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Prediction of Potential Habitat Distribution of Cibotium barometz (L.) J. Sm. Under Climate Change Based on a Multi-Model Ensemble Framework

Biology
Understanding how medicinal plant distributions shift in response to climate change is essential for developing forward-looking conservation strategies. Cibotium barometz (L.) J.
Heng Jiang, Yunfang Zhang, Tao Li, Shuang Zhang, Ying Liu, Yvdan Chen, Minjing Deng, Kunhua Wei, Quan Yang   +8 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Zoning of Integrated Quality Regions for Alpinia officinarum Hance Based on a Multi-Model Evaluation System

Biology
Understanding the spatiotemporal dynamics of medicinal plant distributions and their quality responses under climate change is essential for formulating forward-looking conservation and utilization strategies.
Heng Jiang, Bin Huang, Tao Li, Ying Liu, Shuang Zhang, Quan Yang, Kunhua Wei   +6 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source