Results 31 to 40 of about 169,993 (219)

Preparation of Applications for Inventions Created in the Nuclear, Biological and Chemical Protection Troops

open access: yesВестник войск РХБ защиты, 2023
Patenting of inventions is the basis of the independence of the Russian Federation in the sphere of high technologies, including dual-use ones. The purpose of this work is to review the main approaches to the legal protection of inventions in the Russian
M. V. Supotnitskiy
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Technology mapping: Leukemia Treatment

open access: yesRevista CENIC Ciencias Químicas, 2015
The increase in the incidence of various cancers has been one of the biggest challenges in the global public health for decades. Leukemia is a type of cancer that only in 2008 has affected 351,000 people of the world population.
Luciene Ferreira Gaspar Amaral   +2 more
doaj  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Pitfalls of patenting and state authorization of medicines

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2018
During the lifecycle of a medicine - from its development to consumption - the developer has to go through several stages, such as obtaining the exclusive right for a medicine, obtaining permission to produce the medicine, obtaining permission to ...
V. I. Semenov   +2 more
doaj  

Compulsory Licensing in the Pharmaceutical Market: History and Practice

open access: yesСибирское юридическое обозрение, 2022
In the pharmaceutical industry, the development of a new invention – a drug, the acquisition of a patent and the introduction into civil circulation by the developers spend significant resources in material and time.
K. Yu. Sasykin
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

The Gender Patenting Gap: A Study on the Iberoamerican Countries

open access: yesJournal of Data and Information Science, 2020
This work presents a study on the female involvement in patent applications in all 23 Ibero-American countries that are WIPO members, in order to measure gender inequalities in institutional collaborations and technological fields, across time.
Carvalho Danilo S.   +2 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Synthesis of Network Graph-analytic Reports of Guard and Support of Dynamic Search Processes and Systems

open access: yesБезопасность информационных технологий, 2015
Methods and models of graph-analytic synthesis of network reports of protection and support of essentially nonlinear dynamic search processes and systems are considered.
Sergey Pavlovich Botuz   +1 more
doaj  

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