Results 31 to 40 of about 1,519,224 (329)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Emergence of Digitalization and Artificial Intelligence in the Intellectual Property System
Institutiones Administrationis, 2023 This paper was set to address to what extent intellectual property law is prepared for keeping pace with the rapid development of artificial intelligence and digitalization?
Gábor Szilágyi, Judit Gyarmathy
doaj +1 more source
Copyright as Property in the Post-Industrial Economy: A Research Agenda [PDF]
, 2011 The incentives-for-authors formulation of copyright’s purpose is so deeply ingrained in our discourse and our thought processes that it is astonishingly hard to avoid invoking, even when one is consciously trying not to do so.
Cohen, Julie E.
core +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
The application of GIS to analyse occupier chains and property market filtering [PDF]
, 2010 With funding from the RICS Education Trust, Paul Greenhalgh and Helen King of Northumbria University, UK sought to investigate whether using Geographic Information System (GIS) can enhance the representation and analysis of property occupier chaining ...
Greenhalgh, Paul +2 more
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Results of intellectual activity Academician I.G. Petrovskii Bryansk state university in 2018 in the sphere of industrial property in the direction of «Engineering» [PDF]
Научно-технический вестник Брянского государственного университета, 2019 The article discusses the results of intellectual activity in the field of industrial property, obtained by scientists of the Academician I.G. Petrovskii Bryansk State University in 2018.
Bandurin R.A., Khimich A.V.
doaj +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Безопасность информационных технологий, 2013 The basic methods and the models, the developed software of protection and active support in a network of subjects and objects of the industrial property (inventions and useful models) are considered.
Sergey Pavlovich Botuz +3 more
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