CIIC Biztro Flyer 2014 - print version.pdf
, 2015 Creative Industries Innovation Centre Biztro program flyer, 2014 (extended print ...
Creative Industries Innovation Centre
core
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
20110701 - Media Report 1Apr - 30June11.pdf
, 2015 An internal report of media coverage of the Creative Industries Innovation ...
Creative Industries Innovation Centre
core
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Correction: Effectiveness and Tolerability of Low-Dose Micronized Isotretinoin in Patients with Severe Recalcitrant Nodular Facial Acne in India: A Real-World Retrospective Study Using Electronic Medical Records. [PDF]
Dermatol Ther (Heidelb)Chandrashekar BS +20 more
europepmc +1 more source
20150101 - Media Report 1Oct - 31Dec14.pdf
, 2015 An internal report of media coverage of the Creative Industries Innovation ...
Creative Industries Innovation Centre
core
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
Occupational disease risks in natural resource-based industries among a large cohort of workers in Ontario, Canada. [PDF]
WorkThompson T +5 more
europepmc +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
20141001 - Media Report 1July - 30Sept14.pdf
, 2015 An internal report of media coverage of the Creative Industries Innovation ...
Creative Industries Innovation Centre
core