Results 31 to 40 of about 1,064,410 (251)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Assessment and Forecasting of Energy Efficiency in Economic Sectors in Poland

Energies
The material developed focuses on the analysis of energy efficiency trends in Poland, utilising ODEX indicators for the sectors of industry, transport, households and in general, from 2011 to 2021.
Joanna Żurakowska-Sawa, Mariusz Pyra
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Exploring the Link between Sustainable Practices and Corporate Performance Across Industries

Business Systems Research
The adoption of the Sustainable Development Goals (SDGs) has set a global standard for promoting sustainable practices. However, manufacturing companies need help in adopting these practices due to differences between industries, the need for research ...
Osorio Iris Maria Velez
doaj   +1 more source

Spatial attractiveness towards industrial placement: a parametric index based on spatial-economic territorial exposure metrics

TeMA: Journal of Land Use, Mobility and Environment
The asymmetrical process of industrial development tends to increase regional disparities and result in different patterns of territorial exposure: the amount of support given to activities placed within industrial agglomerates.
Diego Altafini, Valerio Cutini
doaj   +1 more source

Ultrasonic and spectroscopic investigations of molecular interactions in binary mixture of PEG-400 and DMSO at different temperatures [PDF]

Journal of the Serbian Chemical Society
In the present study, the ultrasonic velocity and density data for the binary mixture of polyethylene glycol (PEG)-400 and dimethyl sulfoxide (DMSO), at various concentrations and different temperatures (T, 288.15, 298.15 and 308.15 K), have been ...
Dhiman Monika, Upmanyu Arun, Singh Devinder Pal, Juglan Kailash Chandra   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Nomenclatures industrielles en Grèce. Variations du champ du secteur secondaire et limites de comparabilité

Cahiers Balkaniques, 2018
Vincent Gouzi bend over industrial classifications in Greece, and, through their history and their structure, over the variations of the field of the secondary sector and the limits of comparability.The industrial classifications profoundly evolved in ...
Vincent Gouzi
doaj   +1 more source