Results 31 to 40 of about 4,113,041 (291)
TÜRKİYE'DEKİ TEKNOPARKLARDA KADIN İSTİHDAMI
Kadın geçmişten günümüze daima çalışma hayatının önemli dinamiklerinden biri olmuştur. Kadının çalışma hayatındaki rolü, çalışma ilişkilerinde ortaya çıkan yapısal değişimlerden büyük ölçüde etkilenmiştir.
Gökçe Cerev, Fatih Savuk, Hasan Uzun
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Assessment and Forecasting of Energy Efficiency in Economic Sectors in Poland
The material developed focuses on the analysis of energy efficiency trends in Poland, utilising ODEX indicators for the sectors of industry, transport, households and in general, from 2011 to 2021.
Joanna Żurakowska-Sawa, Mariusz Pyra
doaj +1 more source
Ultrasonic and spectroscopic investigations of molecular interactions in binary mixture of PEG-400 and DMSO at different temperatures [PDF]
In the present study, the ultrasonic velocity and density data for the binary mixture of polyethylene glycol (PEG)-400 and dimethyl sulfoxide (DMSO), at various concentrations and different temperatures (T, 288.15, 298.15 and 308.15 K), have been ...
Dhiman Monika +3 more
doaj +1 more source
Return to R&D Investment and Spillovers in the Chinese Semiconductor Industry: A Tale of Two Segments [PDF]
This study asks how a firm’s market orientation influences its returns to R&D investment and its capability to benefit from external technology opportunities brought about by the globalization of manufacturing and innovation activities. We use a panel of
Chesbrough, Henry +3 more
core +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Vincent Gouzi bend over industrial classifications in Greece, and, through their history and their structure, over the variations of the field of the secondary sector and the limits of comparability.The industrial classifications profoundly evolved in ...
Vincent Gouzi
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source

