Results 31 to 40 of about 1,116,186 (328)

Analysis of cybersecurity threats in Industry 4.0: the case of intrusion detection [PDF]

, 2018
Nowadays, industrial control systems are experiencing a new revolution with the interconnection of the operational equipment with the Internet, and the introduction of cutting-edge technologies such as Cloud Computing or Big data within the organization.
A Moreno, AW Colombo, C McParland, GM Upadhyay, IM Khalil, J Dean, K Zhang, M Brettel, M Chiang, S Wang, T Stock, W Dazhong, X Xu   +12 more
core   +1 more source

Intelligent Autonomous Pollination for Future Farming - A Micro Air Vehicle Conceptual Framework With Artificial Intelligence and Human-in-the-Loop

IEEE Access, 2019
Food security is one of the societal challenge topics. As one-third of all food consumed by humans relies on animal pollination currently, this research provides an emerging solution to food supply reduction caused by population shrinking of natural ...
Yi Chen, Yun Li
doaj   +1 more source

Characterization of Marine Organism Extracellular Matrix-Anchored Extracellular Vesicles and Their Biological Effect on the Alleviation of Pro-Inflammatory Cytokines

Marine Drugs, 2021
Representative marine materials such as biopolymers and bioceramics contain bioactive properties and are applied in regenerative medicine and tissue engineering.
Sung-Han Jo, Seon-Hwa Kim, Changsu Kim, Sang-Hyug Park   +3 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Industry 4.0: The Future of Indo-German Industrial Collaboration [PDF]

, 2017
Industry 4.0 can be described as the fourth industrial revolution, a mega- trend that affects every company around the world. It envisions interconnections and collaboration between people, products and machines within and across enterprises.
Holtkamp, Bernhard, Iyer, Anandi
core  

Customizable Nichrome Wire Heaters for Molecular Diagnostic Applications

Biosensors
Accurate sample heating is vital for nucleic acid extraction and amplification, requiring a sophisticated thermal cycling process in nucleic acid detection.
Juhee Lim, Won Han, Le Tran Huy Thang, Yong Wook Lee, Joong Ho Shin   +4 more
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Cloud-Based Collaborative 3D Modeling to Train Engineers for the Industry 4.0 [PDF]

, 2019
In the present study, Autodesk Fusion 360 software (which includes the A360 environment) is used to train engineering students for the demands of the industry 4.0.
de la Torre Cantero, Jorge, López Chao, Vicente Adrián, Melián Díaz, Dámari, Saorín, José Luis   +3 more
core   +3 more sources

Battery Remaining Useful Life Prediction with Inheritance Particle Filtering

Energies, 2019
Accurately forecasting a battery’s remaining useful life (RUL) plays an important role in the prognostics and health management of rechargeable batteries. An effective forecast is reported using a particle filter (PF), but it currently suffers from
Lin Li, Alfredo Alan Flores Saldivar, Yun Bai, Yun Li   +3 more
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source