Results 21 to 30 of about 56,865 (259)

Evaluating indwelling devices and other risk factors for mortality in invasive Carbapenem-resistant Enterobacterales infections in Georgia, 2012–2019

Antimicrobial Stewardship & Healthcare Epidemiology, 2023
Objective: Carbapenem-resistant Enterobacterales (CRE) infections are a public health threat due to the risk of transmission between patients and high associated mortality.
Lucy S. Witt, Mary Elizabeth Sexton, Gillian Smith, Monica Farley, Jesse T. Jacob   +4 more
doaj   +1 more source

Efficacy of a Fully Implantable Pleural Device in the Management of Complex Pleural Effusions

Current Oncology
VATS talc poudrage is the standard treatment for recurrent pleural effusion, but it is not feasible when the lung does not re-expand, or for fragile patients who are unfit for general anesthesia.
Marco Marcaccini, Simona Sobrero, Federico Vaisitti, Alessandra Russo, Stefano Rudella, Federica Mellone, Chiara Grispi, Luca Errico, Francesco Leo   +8 more
doaj   +1 more source

Shape Memory Polymer‐Based Flexible Pressure Sensor for Real‐Time Venous Thrombosis Monitoring

Advanced Materials Interfaces, EarlyView.
A shape‐memory tubular flexible pressure sensor with a 100‐mesh microstructured SMP‐PLA/MWCNTs sensing layer was developed for PICC‐mounted monitoring of thrombosis‐related pressure changes. The sensor combines high sensitivity (204 kPa−1), a fast response time (28 ms), and conformal catheter fixation and was validated by hydrostatic and ex vivo ...
Yi Chen, Mengtao Huang, Ang Wang, Linsen Tang, Mengting He, Xuejin Li, Shaoxing Qu, Zongrong Wang   +7 more
wiley   +1 more source

Comparing the clinical and cost-effectiveness of various washout policies in preventing catheter associated complications in adults living with long-term catheters: synopsis of the CATHETER II RCT

Health Technology Assessment
Background Approximately 90,000 people in the United Kingdom have a long-term catheter. Use of long-term catheters is associated with common adverse events including blockage of the catheter and symptomatic catheter-associated urinary tract infection ...
Diana Johnson, Sheela Tripathee, David Cooper, Lynda Constable, Muhammad Imran Omar, Sara MacLennan, Seonaidh Cotton, Konstantinos Dimitropoulos, Suzanne Evans, Hashim Hashim, Mary Kilonzo, James Larcombe, Paul Little, Graeme MacLennan, Peter Murchie, Phyo Kyaw Myint, James N’Dow, John Norrie, Catherine Paterson, Karen Powell, Graham Scotland, Nikesh Thiruchelvam, Amanda Young, Mohamed Abdel-fattah   +23 more
doaj   +1 more source

Nursing actions to prevent urinary tract infection associated with long-standing bladder catheter [PDF]

Einstein (São Paulo), 2009
During hospital stay at the Intensive Care Unit (ICU), many treatments and procedures can breakdown the body defense mechanisms leading to infections. Urinary tract infections are the most frequent.
Fabrícia Alves Vieira
doaj  

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

Advanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang, Xiaoxuan Wu, Xuan Chen, Chao Peng, Zihang Li, Shumin Gao, Shiqiu Meng, Jing Dong, Dong Wu, Liying Lv, Ying Han, Yanxue Xue, Lin Lu, Jie Shi, Jianfeng Liu, Yan Sun   +15 more
wiley   +1 more source

An Intravesical Akkermansia muciniphila‐Based Chemo‐Immunotherapeutic Platform for Bladder Cancer

Advanced Science, EarlyView.
Pasteurized Akkermansia muciniphila is engineered into an intravesical F127/doxorubicin platform that couples localized chemotherapy with immune remodeling. By inducing apoptosis, ferroptosis, and immunogenic cell death, this chemo‐immunotherapeutic system enhances dendritic‐cell maturation, antigen cross‐presentation, and tumor‐specific CD8+ T‐cell ...
Rongkang Li, Anguo Zhao, Qi Zhuang, Lei Peng, Rui Liang, Jiadong Zhao, Yang Liu, Dashi Deng, Peng Yu, Xiqi Peng, Shaohua Zhang, Song Wu   +11 more
wiley   +1 more source

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

Advanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong, Xingjin Li, Tao Hu, Qianqian Lu, Xiaoxu Zhang, Xi Chen, Yifan Luo, Zhong Zuo, Ronald Man Yeung Wong, Miao Xu, Tiancong Zhao, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Timing of Antimicrobial Lock Replacement for Gram-Positive Port Infections: Results of a Randomized Trial

Antibiotics
Background: Conservative management of port-related bacteremia often includes locally administered antimicrobials, known as antimicrobial lock therapy (ALT). Current guidelines recommend daily replacement of antimicrobial lock solutions (ALSs).
César Bustos, José R. Yuste, Aitziber Aguinaga, Asunción Parra, Francisco Carmona-Torre, José R. Azanza, Carlos Lacasa, José L. Del Pozo   +7 more
doaj   +1 more source

A novel rat model of pulmonary artery embolism and the application value of lung ultrasound B‐lines in early‐stage pulmonary embolism

Animal Models and Experimental Medicine, EarlyView.
We report a novel embolus‐induced PE rat model prepared via the inferior vena cava under ultrasound guidance. The embolus employed featured a tubular plastic casing filled with thrombus. By minimizing the contact surface between plasmin and thrombus, it effectively restrains the elevated plasmin activity in rats.
Huide Ma, Shuangrui Wang, Honghui Li, Yaxing Zhang, Yuman Gao, Jie Zhou, Xia Xu, Rong Wu   +7 more
wiley   +1 more source