Results 191 to 200 of about 179,595 (268)

Autism spectrum disorder burden across 798 locations, 1990-2023: frontier and inequality mapping in the context of child injury prevention and safety promotion. [PDF]

open access: yesFront Public Health
Liang X   +14 more
europepmc   +1 more source

Performance improvement of discrete‐time linear‐quadratic regulators applied to uncertain linear systems using the Tikhonov regularization method

open access: yesAsian Journal of Control, EarlyView.
Abstract The linear‐quadratic regulator (LQR) problem of optimal control of an uncertain discrete‐time linear system (DTLS) is revisited in this paper from the perspective of Tikhonov regularization. We show that an optimally chosen regularization parameter reduces, compared to the classical LQR, the values of a scalar error function, as well as the ...
Fernando Pazos, Amit Bhaya
wiley   +1 more source

Subspace‐Based System Identification From Binary Measurements

open access: yesAsian Journal of Control, EarlyView.
ABSTRACT This paper is concerned with subspace identification from binary measurements for systems whose dynamical behavior can be splited into a deterministic and a stochastic subsystem. An identification algorithm is detailed. The main contribution of the proposed identification algorithm lies in the identification of both the deterministic subsystem
Alex Ali Mestrah   +2 more
wiley   +1 more source

Cost‐effectiveness of DPYD genotyping prior to fluoropyrimidine‐based treatment for colorectal cancer in Wales

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Background Regulatory guidance in the United Kingdom advises DPYD genotyping prior to fluoropyrimidine‐based treatment. This economic evaluation estimated the costs and outcomes associated with DPYD screening prior to prescribing fluoropyrimidines for colorectal cancer in Wales and also considers additional variants to those included in ...
Catrin O. Plumpton   +8 more
wiley   +1 more source

Benzodiazepines use in primary care England: Prescribing patterns and adverse consequences

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Benzodiazepines (BZDs) are commonly prescribed for anxiety and insomnia but carry risks such as dependence, adverse drug reactions (ADRs) and mortality. Despite deprescribing efforts, the influence of recent prescribing trends, COVID‐19 and adverse outcomes on prescribing patterns in England remains uncertain.
Alvina Chaudhry   +3 more
wiley   +1 more source

Towards appropriate guidance for the ethical challenges of environmentally sustainable prescribing

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
The environmental impact of medicines poses a significant threat to planetary and public health, making it essential to integrate environmental sustainability into prescribing practices. While the most effective measures to reduce environmental impact, such as reducing unnecessary prescriptions and medication waste, are consistent with appropriate ...
Joost D. Piët   +22 more
wiley   +1 more source

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