Results 101 to 110 of about 10,230 (291)

Inertial Microfluidics: Mechanisms and Applications

, 2016
In microfluidics, the typical sample volume is in the order of nL, which is incompatible with the common biosample volume in biochemistry and clinical diagnostics (usually ranging from 1 μL to approximately 1 mL). The recently emerged inertial microfluidic technology offers the possibility to process large volume (∼mL) of biosample by well-defined ...
Zhang, Jun, Li, Weihua, Alici, Gursel
openaire   +3 more sources

Staged inertial microfluidic focusing for complex fluid enrichment [PDF]

RSC Advances, 2015
A staged microfluidic inertial focusing device capable of high-yield, high-throughput complex fluid enrichment has been developed for integrated microfluidic cellular assays and biological micro total analysis systems.
Reece, Amy E., Oakey, John, Kaastrup, Kaja, Sikes Johnson, Hadley   +3 more
openaire   +4 more sources

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Flow optimization study of a batch microfluidics PET tracer synthesizing device. [PDF]

, 2010
We present numerical modeling and experimental studies of flow optimization inside a batch microfluidic micro-reactor used for synthesis of human-scale doses of Positron Emission Tomography (PET) tracers.
Daridon, Antoine, Elizarov, Arkadij M, Heath, James R, Huang, Jiang, Kolb, Hartmuth C, Meinhart, Carl, Miraghaie, Reza, van Dam, R Michael   +7 more
core   +4 more sources

A Quantitative Printability Framework for Programmable Assembly of Pre‐Vascular Patterns via Laser‐Induced Forward Transfer

Advanced Healthcare Materials, EarlyView.
Laser‐Induced Forward Transfer (LIFT) is presented as a powerful micropatterning tool. An objective printability framework is developed to assess optimal printing parameter combinations. The technology is further explored for its ability to deterministically deposit microdroplets at predefined locations following CAD designs, enabling the patterning of
Cécile Bosmans, Núria Ginés Rodriguez, Ulisses Jesús Gutiérrez Hernández, David Fernandez Rivas, Marcel Karperien, Jos Malda, Liliana Moreira Teixeira, Riccardo Levato, Jeroen Leijten   +8 more
wiley   +1 more source

Design and fabrication of a centrifugally driven microfluidic disk for fully integrated metabolic assays on whole blood [PDF]

, 2006
For the first time, we present a novel and fully integrated centrifugal microfluidic “ lab-on-a-disk” for rapid metabolic assays in human whole blood.
Brenner, T., Ducrée, Jens, Grumann, M., Riegger, L., Steigert, J., Zengerle, Roland   +5 more
core   +2 more sources

Cell sorting actuated by a microfluidic inertial vortex

Lab on a Chip, 2019
Vortex-actuated cell sorting: a new cell sorter, based on a transient microfluidic vortex generated by a thermal vapour bubble.
Robyn H. Pritchard, Alexander A. Zhukov, James N. Fullerton, Andrew J. Want, Fred Hussain, Mette F. la Cour, Mikhail E. Bashtanov, Richard D. Gold, Anthony Hailes, Edward Banham-Hall, Salman Samson Rogers   +10 more
openaire   +4 more sources

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

PiP‐Plex: A Particle‐in‐Particle System for Multiplexed Quantification of Proteins Secreted by Single Cells

Advanced Materials, EarlyView.
Detecting proteins secreted by a single cell while retaining its viability remains challenging. A particles‐in‐particle (PiPs) system made by co‐encapsulating barcoded microparticles (BMPs) with a single cell inside an alginate hydrogel particle is introduced.
Félix Lussier, Byeong‐Ui Moon, Mojra Janta‐Polczynski, Yonatan Morocz, Fabian Svahn, Molly Shen, Ljuboje Lukic, Lidija Malic, Teodor Veres, Andy Ng, David Juncker   +10 more
wiley   +1 more source