Fast Process Development Made Possible Using an Easy to Duplicate Integrated Microfluidic Platform
We present a next‐generation microfluidic platform that accelerates membrane process development through integrated flow control, inline XRF monitoring, and machine‐learning‐assisted optimization. Demonstrated with a charged nanosheet membrane selectively recovering silver from real e‐waste leachates, the system enables rapid, Iow‐consumption, real ...
Iyo Baudouy +7 more
wiley +1 more source
New insights into the physics of inertial microfluidics in curved microchannels. II. Adding an additive rule to understand complex cross-sections. [PDF]
Rafeie M +5 more
europepmc +1 more source
• EV content maintains cellular homeostasis and is involved in several disease onset and progression. • miRNA export in EVs depends on: RNA‐binding proteins recognizing motif sequences and on epitranscriptomic modifications. • The disclosure of delivery mechanisms is crucial for developing personalized EV‐based therapeutic tools. ABSTRACT Extracellular
Sabrina Garbo +4 more
wiley +1 more source
In many chemical reactions, short‐lived radical intermediates play a crucial role, while detecting them in situ remains challenging. The optically readable electronic spin of NV centers in diamond is a nanoscale sensor for such radical species. We demonstrate the successful in situ detection of the nitroxide radical 2,2,6,6‐TEMPO using NV center‐based ...
Emma Herbst +5 more
wiley +1 more source
Numerical investigation of heterogeneous soft particle pairs in inertial microfluidics.
Owen B, Thota K, Krüger T.
europepmc +1 more source
Label-free Neutrophil Enrichment from Patient-derived Airway Secretion Using Closed-loop Inertial Microfluidics. [PDF]
Ryu H +5 more
europepmc +1 more source
3D Hydrodynamic Flow Lithography
ABSTRACT Continuous‐ and stop‐flow lithography are widely used to fabricate multi‐dimensional microstructures whose cross‐sectional morphology is dictated by the flow profile of multiple co‐flowing streams. Here, we introduce three‐dimensional hydrodynamic flow lithography (3D HFL), a platform for programmable generation of multi‐layered flow profiles ...
Yiying Zou +5 more
wiley +1 more source
Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans +7 more
wiley +1 more source
Electrically Readable Lateral Flow Assay Using Organic Transistors for Diagnostic Applications
Electrolyte‐gated organic field‐effect transistors (EGOFETs) are integrated with lateral flow (LF) paper fluidics to create a reusable, portable, and low‐cost point‐of‐care (PoC) diagnostic test. The devices are validated for Human Immunoglobulin G detection, achieving high sensitivity (0.1 fm), selectivity, and reproducibility with rapid results in 20–
María Jesús Ortiz‐Aguayo +4 more
wiley +1 more source
Elasto-inertial microfluidics for bacteria separation from whole blood for sepsis diagnostics. [PDF]
Faridi MA +5 more
europepmc +1 more source

