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A review on the mechanics of inertial microfluidics
2021In a number of microfluidics-based systems where the Reynolds number is in an intermediate range, both viscosity and inertia are significant, and thus, plenty of interesting effects appear including inertial motion and secondary flow. In recent years, this rapidly expanding area of science has opened a new window of possibilities for micro-particle ...
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Control of inertial microfluidics
2015The young field of inertial microfluidics investigates fluid inertia to enhance the performance of microfluidic devices. The scope of inertial microfluidics expanded rapidly to cover a diverse set of applications, after the first devices were proposed in the early 2000s.
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Particle dynamics in inertial microfluidics
2020Die inertiale Mikrofluidik beschäftigt sich mit laminaren Strömungen von Flüssigkeiten durch mikroskopische Kanäle, bei denen die Trägheitseffekte der Flüssigkeit nicht vernachlässigt werden können. Befinden sich Teilchen in diesen inertialen Strömungen, ordnen sie sich von selbst an bestimmten Positionen auf der Querschnittsfläche an.
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Plasma Isolation in a Syringe by Conformal Integration of Inertial Microfluidics
Annals of Biomedical Engineering, 2020A thermoplastic microfluidic substrate is conformally integrated onto the cylindrical barrel of a conventional venipuncture syringe, forming a spiral inertial separation element supporting the isolation of plasma from diluted whole blood. The cylindrical shape of the syringe itself serves to define the flow path required for inertial separation by ...
Jung Y. Han, Don L. DeVoe
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Inertial microfluidics for flow cytometry
SPIE Proceedings, 2010Inertial components of the Navier-Stokes equations are usually not considered in microfluidic flows but have recently been shown to be of great practical use for continuous manipulation of particles and cells. After introducing the physical basis of the counter-intuitive self focusing of particles in a single inlet flow, I will discuss our current ...
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Controllable trajectory of inertial focusing in microfluidics
Microelectronic Engineering, 2015Inertial focusing in microfluidics has been widely utilized to sort cells based on cell specific properties for clinical assay, the detection of environmental pathogenic microorganisms and cell biology research. Especially, cell inertial focusing in microchannels, containing slant groove structures, has been utilized for cell separation, enrichment and
Dianshen Yang +3 more
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Inertial microfluidics and its applications in hematology
2019This chapter summarizes the theoretical background of inertial microfluidics that is important for applications in the field of hematology. The inertial microfluidics field has emerged from the finding of the importance of fluid inertia in microfluidic flows. The chapter reviews two main applications of inertial microfluidics in hematology: separations
Wonhee Lee +3 more
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Inertial Microfluidic Cell Separation
2016The ability to rapidly manipulate cells within microfluidic devices has been a fascinating goal for engineers across disciplines over the past two decades. With highly controllable flows and the ability to create microstructures on the same scale as cells, a large variety of technologies to sort and separate cells have been rapidly developed.
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Inertial and elasto-inertial microfluidics offer promising platforms for high-throughput, label-free cell sorting by leveraging hydrodynamic forces to focus particles and cells within confined flows. This dissertation presents a computational investigation into the mechanisms governing cell migration and focusing in such systems, with an emphasis on ...
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