Results 21 to 30 of about 154,264 (216)

Infant mortality in a very low birth weight cohort from a public hospital in Rio de Janeiro, RJ, Brazil

Revista Brasileira de Saúde Materno Infantil, 2013
OBJECTIVES: to evaluate infant mortality in very low birth weight newborns from a public hospital in Rio de Janeiro, Brazil (2002-2006). METHODS: a retrospective cohort study was performed using the probabilistic linkage method to identify infant ...
Regina Coeli Azeredo Cardoso, Patrícia Viana Guimarães Flores, Cláudia Lima Vieira, Kátia Vergetti Bloch, Rejane Sobrino Pinheiro, Sandra Costa Fonseca, Claudia Medina Coeli   +6 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Maternal socioeconomic status and infant mortality with low birth weight as a mediator: an inter-country comparison between Scotland and Denmark using administrative data

International Journal of Population Data Science, 2017
Objectives Higher rates of infant mortality in the UK than in the Nordic countries are partly explained by wider socio-economic disparities in the UK. We examined the extent to which low birth weight mediates the association between socioeconomic status (
Yongfu Yu, Maximiliane Verfuerden, Pia Hardelid, Ania Zylbersztejn, Zeyan Liew, Jørn Olsen, Ruth Gilbert, Jiong Li, Bo Fu   +8 more
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Maternal serum albumin in the late trimester and birth weight: a cross-sectional study from Jiangxi, China.

PLoS ONE
BackgroundThe links of maternal serum albumin (ALB) concentration in the late trimester and infant birth weight remain equivocal. Accordingly, we focused on the investigation of the correlation of maternal serum albumin concentration and infant birth ...
Jun Xiong, Huan Li, Jian-Min Zhang, Shi-Qi Li, Chang Ge, Hui-Xin Zheng, Xiao-Qing Tan, Jia-Wei Zheng, Xiao-Ju He, Shu-Ying Zhu   +9 more
doaj   +1 more source

Follow-up evaluation of children with birth weight less than or equal to 2,000 g

São Paulo Medical Journal
CONTEXT: During the first year of life, the growth process is highly vulnerable to several impairing factors that need to be understood. OBJECTIVE: To perform follow-up evaluation on newborns weighing less than or equal to 2,000 g in a population of low ...
Marcia de Freitas, Arnaldo Siqueira, Conceição Aparecida de Mattos Segre   +2 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Low birth weight and its association factors in Iran: according world health organization model

Journal of Rehabilitation, 2012
Objective: Birth weight is one of the most important ,simplest and common determinations for assessments infants status in each country. this study has been designed to investigate the articles that published in its prevalence and related factors ...
zohreh Mahmoudi, Masoud Karimlou, Homeira Sajjadi, Ma'soumeh Dejman, Marveh Vameghi   +4 more
doaj  

Adaptive Foam 3D Printing of Ultralight and Multifunctional Materials

Advanced Engineering Materials, EarlyView.
Adaptive foam 3D printing, enabled by expandable microspheres, imparts cellular structures to thermoplastic and thermosetting polymers, manufactured through a variety of processes including fused filament fabrication, direct ink writing, digital light processing, and inkjet printing.
Nariman Rajabifar, Amir Ameli
wiley   +1 more source