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The Importance of a Healthy Microbiome in Pregnancy and Infancy and Microbiota Treatment to Reverse Dysbiosis for Improved Health [PDF]

Antibiotics, 2023
Background: The microbiome of newborn infants during the first 1000 days, influenced early on by their mothers’ microbiome health, mode of delivery and breast feeding, orchestrates the education and programming of the infant’s immune system and ...
Herbert L. DuPont, Madeleine Mary Hines Salge   +1 more
doaj   +3 more sources

Impact of prenatal phthalate exposure on newborn metabolome and infant neurodevelopment. [PDF]

Nat Commun
We evaluated associations among exposure to prenatal phthalate metabolites, perturbations of the newborn metabolome, and infant neurobehavioral functioning in mother-newborn pairs enrolled in the Atlanta African American Maternal-Child Cohort during 2016–
Hoffman SS, Tang Z, Dunlop A, Brennan PA, Huynh T, Eick SM, Barr DB, Rushing B, McRitchie SL, Sumner S, Taibl KR, Tan Y, Panuwet P, Lee GE, Eatman J, Corwin EJ, Ryan PB, Jones DP, Liang D.   +18 more
europepmc   +2 more sources

Early vasopressin infusion improves oxygenation in infants with congenital diaphragmatic hernia

Frontiers in Pediatrics, 2023
ObjectiveCongenital Diaphragmatic Hernia (CDH) is a complex disease including a diaphragmatic defect, lung hypoplasia, and pulmonary hypertension. Despite its increasing use in neonates, the literature on the use of vasopressin in neonates is limited ...
Irma Capolupo, Domenico Umberto De Rose, Francesca Mazzeo, Francesca Monaco, Paola Giliberti, Francesca Landolfo, Alessandra Di Pede, Alessandra Toscano, Andrea Conforti, Pietro Bagolan, Pietro Bagolan, Andrea Dotta   +11 more
doaj   +1 more source

Multisystem Inflammatory Syndrome in Neonates Born to Mothers with SARS-CoV-2 Infection (MIS-N) and in Neonates and Infants Younger Than 6 Months with Acquired COVID-19 (MIS-C): A Systematic Review

Viruses, 2022
(1) Introduction: There is an increasing literature describing neonates born to mothers with SARS-CoV-2 infection (MIS-N) and infants infected with SARS-CoV-2 who presented with a severe disease (MIS-C).
Domenico Umberto De Rose, Flaminia Pugnaloni, Monica Calì, Sara Ronci, Stefano Caoci, Chiara Maddaloni, Ludovica Martini, Alessandra Santisi, Andrea Dotta, Cinzia Auriti   +9 more
doaj   +1 more source

The Role of Lung Function Testing in Newborn Infants With Congenital Thoracic Arterial Anomalies

Frontiers in Pediatrics, 2021
Introduction: Congenital thoracic arterial anomalies (CTAAs), such as complete or incomplete vascular rings, pulmonary artery sling, and innominate artery compression syndrome, may cause severe tracheomalacia and upper airway obstruction.
Claudia Columbo, Francesca Landolfo, Domenico Umberto De Rose, Anna Claudia Massolo, Aurelio Secinaro, Teresa Pia Santangelo, Marilena Trozzi, Cosimo Marco Campanale, Alessandra Toscano, Irma Capolupo, Pietro Bagolan, Andrea Dotta   +11 more
doaj   +1 more source

SARS-CoV-2 Vaccines during Pregnancy and Breastfeeding: A Systematic Review of Maternal and Neonatal Outcomes

Viruses, 2022
(1) Objective: This systematic review summarizes current knowledges about maternal and neonatal outcomes following COVID-19 vaccination during pregnancy and breastfeeding.
Domenico Umberto De Rose, Guglielmo Salvatori, Andrea Dotta, Cinzia Auriti   +3 more
doaj   +1 more source

Maternal–Fetal Infections (Cytomegalovirus, Toxoplasma, Syphilis): Short-Term and Long-Term Neurodevelopmental Outcomes in Children Infected and Uninfected at Birth

Pathogens, 2022
(1) Background: Infections in pregnancy can lead to miscarriage, premature birth, infections in newborns, and developmental disabilities in babies. Infected infants, symptomatic at birth, can have long-term sequelae, and asymptomatic babies are also at ...
Cinzia Auriti, Silvia Bucci, Domenico Umberto De Rose, Luana Coltella, Alessandra Santisi, Ludovica Martini, Chiara Maddaloni, Iliana Bersani, Simona Lozzi, Francesca Campi, Concettina Pacifico, Martina Balestri, Daniela Longo, Teresa Grimaldi   +13 more
doaj   +1 more source

Operative Management of Neonatal Lymphatic Malformations: Lesson Learned From 57 Consecutive Cases

Frontiers in Pediatrics, 2021
Aim of the study: Lymphatic malformations (LMs) are rare entities, sometimes difficult to treat, that may be life-threatening when intricately connected to airway structures.
Marianna Scuglia, Andrea Conforti, Andrea Conforti, Laura Valfrè, Giorgia Totonelli, Chiara Iacusso, Barbara D. Iacobelli, Duino Meucci, Milena Viggiano, Fabio Fusaro, Andrea Diociaiuti, Francesco Morini, May El Hachem, Pietro Bagolan, Pietro Bagolan   +14 more
doaj   +1 more source

Technical Considerations and Protocol Optimization for Neonatal Salivary Biomarker Discovery and Analysis

Frontiers in Pediatrics, 2021
Non-invasive techniques to monitor and diagnose neonates, particularly those born prematurely, are a long-sought out goal of Newborn Medicine. In recent years, technical advances, combined with increased assay sensitivity, have permitted the high ...
Elizabeth Yen, Elizabeth Yen, Tomoko Kaneko-Tarui, Jill L. Maron, Jill L. Maron   +4 more
doaj   +1 more source

Defective Leukocyte β2 Integrin Expression and Reactive Oxygen Species Production in Neonates

Children, 2022
Neonates are highly susceptible to bacterial infections, which represent a major source of mortality and morbidity in this age category. It is recognized that β2 integrins play a critical role in innate immunity by mediating leukocyte vascular adhesion ...
Irma Capolupo, Domenico Umberto De Rose, Roberto Pascone, Olivier Danhaive, Marcello Orzalesi   +4 more
doaj   +1 more source