Results 71 to 80 of about 362,289 (308)

KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through Regulation of Wnt/β‐Catenin Signaling Pathway

open access: yesAdvanced Science, EarlyView.
In KLF1‐on (neonatal and Klf1 overexpression hearts) models, KLF1 regulates Wnt/β‐catenin signaling pathway and the expression of cell proliferation‐related genes via transcriptional and epigenetic mechanisms, which induces cardiomyocyte proliferation and cardiac regeneration in mice after myocardial infarction.
Yanglin Hao   +19 more
wiley   +1 more source

INFECTIONS OF THE NEWBORNS: ETIOLOGY AND EPIDEMIOLOGY [PDF]

open access: yesRomanian Journal of Pediatrics, 2008
Infections are a frecvent and important cause of morbidity and mortality in the newborn period. Infections in the newborn infant may be required in utero (congenital), at the terme/or birth (perinatal), or after birth and during the neonatal period ...
Valeriu Popescu
doaj   +1 more source

Ultrasound Super‐Resolution Imaging of Neonatal Cerebral Vascular Reorganization

open access: yesAdvanced Science, Volume 12, Issue 12, March 27, 2025.
The scale of neonatal microvasculature is currently beyond the resolution of clinical imaging techniques. In this study, ultrasound localization microscopy is used to observe the microvasculature in neonates undergoing treatments for life‐threatening vascular malformations.
Simone Schwarz   +19 more
wiley   +1 more source

A companion to the preclinical common data elements for rodent models of pediatric acquired epilepsy: A report of the TASK3‐WG1B, Pediatric and Genetic Models Working Group of the ILAE/AES Joint Translational Task Force

open access: yesEpilepsia Open, EarlyView., 2022
Abstract Epilepsy syndromes during the early years of life may be attributed to an acquired insult, such as hypoxic–ischemic injury, infection, status epilepticus, or brain trauma. These conditions are frequently modeled in experimental rodents to delineate mechanisms of epileptogenesis and investigate novel therapeutic strategies.
Anna‐Maria Katsarou   +7 more
wiley   +1 more source

A novel association between cerebral sinovenous thrombosis and nonketotic hyperglycinemia in a neonate [PDF]

open access: yesKorean Journal of Pediatrics, 2015
Lethargy in newborns usually indicates central nervous system dysfunction, and many conditions such as cerebrovascular events, infections, and metabolic diseases should be considered in the differential diagnosis.
Sadık Yurttutan   +5 more
doaj   +1 more source

Classification of Neurodevelopmental Age in Normal Infants Using 3D-CNN based on Brain MRI [PDF]

open access: yesarXiv, 2019
Human brain development is rapid during infancy and early childhood. Many disease processes impair this development. Therefore, brain developmental age estimation (BDAE) is essential for all diseases affecting cognitive development. Brain magnetic resonance imaging (MRI) of infants shows brain growth and morphologic patterns during childhood. Therefore,
arxiv  

Grading the severity of hypoxic-ischemic encephalopathy in newborn EEG using a convolutional neural network [PDF]

open access: yesarXiv, 2020
Electroencephalography (EEG) is a valuable clinical tool for grading injury caused by lack of blood and oxygen to the brain during birth. This study presents a novel end-to-end architecture, using a deep convolutional neural network, that learns hierarchical representations within raw EEG data.
arxiv  

Endothelial Cpt1a Inhibits Neonatal Hyperoxia‐Induced Pulmonary Vascular Remodeling by Repressing Endothelial‐Mesenchymal Transition

open access: yesAdvanced Science, Volume 12, Issue 11, March 20, 2025.
Endothelial‐mesenchymal transition (EndoMT) causes pulmonary vascular remodeling in a murine model of bronchopulmonary dysplasia‐associated pulmonary hypertension. Endothelial reduction of carnitine palmitoyltransferase 1a (Cpt1a) is identified as a novel mechanism of lung EndoMT.
Xiaoyun Li   +14 more
wiley   +1 more source

Infant Mortality in Novo Hamburgo: Associated Factors and Cardiovascular Causes

open access: yesArquivos Brasileiros de Cardiologia, 2015
Background: Infant mortality has decreased in Brazil, but remains high as compared to that of other developing countries. In 2010, the Rio Grande do Sul state had the lowest infant mortality rate in Brazil.
Camila de Andrade Brum   +2 more
doaj   +1 more source

Nanopore Sequencing Solves an Elusive Case of Sotos Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Sotos syndrome is a rare genetic disorder characterized by distinctive facial features, including a broad and prominent forehead, dolichocephaly, and learning disabilities ranging from mild to severe intellectual impairment. Affected individuals often show overgrowth in height and head circumference over two standard deviations.
Pasquale Di Letto   +52 more
wiley   +1 more source

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