Results 211 to 220 of about 1,481,989 (336)

Video‐based diagnostics supported by artificial intelligence as an opportunity to address the epilepsy diagnostic gap: A narrative review

open access: yesEpilepsia, EarlyView.
Abstract Despite advancements in epilepsy care, a substantial diagnostic gap persists, particularly in resource‐limited settings. This narrative review explores the potential of video‐based diagnostics augmented by artificial intelligence (AI) to address this gap by enabling earlier and more accessible seizure detection and classification.
Gadi Miron   +7 more
wiley   +1 more source

Newborn and infant.

open access: yesRinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics, 1991
openaire   +2 more sources

Evolution of the European Medicines Agency clinical guidelines for epilepsy drug development between 2010 and 2025: A comparative analysis by the ILAE Task Force on Regulatory Affairs

open access: yesEpilepsia, EarlyView.
Abstract Objective The latest European Medicines Agency (EMA) guideline on the clinical investigation of medicines to treat epileptic disorders was adopted by the EMA Committee for Medicinal Products for Human Use in 2025. We compared this guideline with the previous version (2010), highlighting areas where significant revisions were introduced ...
Stéphane Auvin   +7 more
wiley   +1 more source

KCNJ4 variants disrupt inward‐rectifier potassium channel function and cause refractory epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy is a common neurological disorder with a strong genetic basis, most frequently arising from ion channel dysfunction. Although multiple inwardly rectifying potassium (Kir) channels have been implicated in epileptogenesis, the contribution of KCNJ4, which encodes the Kir2.3 channel, has not previously been established in human
Hu Pan   +20 more
wiley   +1 more source

The COVID generation: the neurodevelopmental consequences of in-utero COVID-19 exposure. [PDF]

open access: yesBrain Behav Immun
Weiner S   +9 more
europepmc   +1 more source

Lactate receptor HCAR1 in neonatal hypoxic–ischemic seizures

open access: yesEpilepsia, EarlyView.
Abstract Hydroxycarboxylic acid receptor 1 (HCAR1) is a G‐protein‐coupled lactate receptor expressed in the brain and plays a role in neuronal excitability and repair after injury. Hypoxic–ischemic encephalopathy (HIE) is the most common cause of brain injury and seizures in term neonates.
Jennifer Burnsed   +11 more
wiley   +1 more source

Long‐term safety of early discontinuation of antiseizure medication after resolution of acute provoked neonatal seizures

open access: yesEpilepsia, EarlyView.
Abstract Objective To assess long‐term safety of antiseizure medication (ASM) discontinuation after resolution of acute provoked neonatal seizures and prior to hospital discharge. Methods Prospective, observational, comparative effectiveness cohort study of neonates with acute provoked seizures born from July 2015 to March 2018, and followed until ...
Hannah C. Glass   +16 more
wiley   +1 more source

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