STING Agonists and How to Reach Their Full Potential in Cancer Immunotherapy
Advanced Science, EarlyView.STING agonists show promise in preclinical studies in boosting an anti‐tumor response using the immune system. However, different limitations remain, and future research is needed to better understand how STING activation impacts the tumor microenvironment, identify effective combination strategies, and determine the best tumor types for STING agonist ...
Laura Gehrcken +3 more
wiley +1 more source
Intestinal Dysbiosis and the Developing Lung: The Role of Toll-Like Receptor 4 in the Gut-Lung Axis. [PDF]
, 2020 BackgroundIn extremely premature infants, postnatal growth restriction (PNGR) is common and increases the risk of developing bronchopulmonary dysplasia (BPD) and pulmonary hypertension (PH). Mechanisms by which poor nutrition impacts lung development are
Chiamvimonvat, Nipavan +10 more
core
Estimation of causal effects using instrumental variables with nonignorable missing covariates: Application to effect of type of delivery NICU on premature infants [PDF]
Annals of Applied Statistics 2014, Vol. 8, No. 1, 48-73, 2014 Understanding how effective high-level NICUs (neonatal intensive care units that have the capacity for sustained mechanical assisted ventilation and high volume) are compared to low-level NICUs is important and valuable for both individual mothers and for public policy decisions.
arxiv +1 more source
Vitamin D Status in Premature Infants at Risk of Metabolic Bone Disease of Prematurity [PDF]
Maternal and Pediatric Nutrition, 2017 Objectives: The purpose of this study is to report the vitamin D status in a group of premature infants with increased risk of MBD and to describe the relationship between their vitamin D status and intake. Methods: Retrospective descriptive study in in a level IV neonatal intensive care unit. Results: One hundred and fifty-two subjects were included
Kelly A +2 more
openaire +1 more source
Infection and Drug Resistance, 2022 Aiyun Li,1,* Ming Fang,2,* Dongjie Hao,1 Qiaoai Wu,1 Yaqi Qian,1 Hao Xu,3,4 Bo Zhu1 1Department of Clinical Medicine, The Women’s Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 2Institute of ...
Li A +6 more
doaj
Statistical models of economic burden : a case study in medicine [PDF]
, 2019 Purpose: The main aim of this article is to use statistical methods for the estimation of the economic burden and the survival rate of deeply premature babies.
Gindullin, R. V. +3 more
core
Computational Challenges in Non-parametric Prediction of Bradycardia in Preterm Infants [PDF]
arXiv, 2020 Infants born before 37 weeks of pregnancy are considered to be preterm. Typically, preterm infants have to be strictly monitored since they are highly susceptible to health problems like hypoxemia (low blood oxygen level), apnea, respiratory issues, cardiac problems, neurological problems as well as an increased chance of long-term health issues such ...
arxiv
Immunoprophylaxis of infectious diseases in premature infants
Pediatric pharmacology, 2018 Premature infants are especially in need of timely and effective specific immunoprophylaxis due to their vulnerability to infectious diseases. The article describes the basic principles for vaccination of premature infants used in healthcare by the leading countries of the world.
Alexander A. Baranov +7 more
openaire +4 more sources
Chronic respiratory disease in premature infants caused by Chlamydia trachomatis. [PDF]
Journal of Clinical Pathology, 1986 The relation between chronic respiratory disease and infection with Chlamydia trachomatis in premature infants was investigated to ascertain the aetiological importance of intrauterine C trachomatis infection and chronic respiratory disease in premature infants.
K. Numazaki +5 more
openaire +3 more sources
The Iowa Perinatal Letter, April-May-June 2008, Vol. 29, no. 2 [PDF]
, 2008 This newsletter from The Department of Public Health about perinatal health care and ...
core