Results 131 to 140 of about 387,291 (285)

Prenatal vitamin D levels and postpartum hemorrhage in a rural Alaska cohort

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To examine the relationship between prenatal vitamin D serum levels and postpartum bleeding. Methods We conducted a retrospective electronic health record cohort study of pregnant Alaska Native and American Indian (ANAI) people in southwestern Alaska who had at least one prenatal vitamin D level measurement recorded and had a vaginal
Reinou S. Groen, Julie A. Beans, Gretchen Day, Lauryl Torkelson, Anjali Madeira, David Compton, Joseph Klejka, Jennifer Shaw   +7 more
wiley   +1 more source

Maternal RSV vaccination for infant protection: A systematic review and meta‐analysis of phase 3 trials with an integrated economic evaluation

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Respiratory syncytial virus (RSV) is a leading cause of hospitalization and mortality in early infancy. Maternal immunization offers a preventive strategy, but uncertainties regarding safety and economic value have limited its implementation.
Johnatan Torres‐Torres, Lourdes Rojas‐Zepeda, José Rafael Villafan‐Bernal, Raigam Martinez‐Portilla, Salvador Espino‐y‐Sosa, Pablo Cerda‐Flores, Elsa Romelia Moreno‐Verduzco, Irma Eloisa Monroy‐Muñoz, Ameyran Yolanda Gonzalez‐Guerrero, Juan Mario Solis‐Paredes, Javier Perez Duran   +10 more
wiley   +1 more source

Effects of integrated programs for substance‐involved mothers on infant and child development outcomes: A systematic review and meta‐analysis

Infant Mental Health Journal: Infancy and Early Childhood, EarlyView.
Abstract Maternal substance use is a pressing public health issue that confers risk for maternal health, the parent‐infant relationship, and child development. Integrated interventions that jointly address maternal substance use and child development have shown promise for enhancing child outcomes.
Sophie Barriault, Mary Motz, Lamia Firasta, Hannah McDowell, Patrick R. Labelle, Nancy Poole, Nicole Racine   +6 more
wiley   +1 more source

Immunomodulatory and regenerative potentials of breast milk, prematurity and children’s heart

Медицинская иммунология
Recent expansion of fundamental knowledge on the physiology of lactation, and breast milk exosomes, stem cell biology, mother-child interactions from prenatal period to postnatal development requires a progressive, dynamic view from the scientific ...
E. N. Pavlyukova, M. V. Kolosova, G. V. Neklyudova, R. S. Karpov   +3 more
doaj   +1 more source

New insights into applications of base editor in hereditary disorders

Interdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai, Linhui Zhang, Liqing Li, Yue Liu, Canbin Lv, Yan Shi, Jianyuan Zhao, Dingwei Ye, Yuanyuan Qu   +8 more
wiley   +1 more source

Saliva as a TDM matrix and its application in the model‐informed precision dosing

The Journal of Clinical Pharmacology, EarlyView.
Abstract This study reviews the main points of saliva as a therapeutic drug monitoring (TDM) matrix, its advantages and limitations, the methods of saliva sample collection and testing, the types of drugs in saliva TDM, and the methods of establishing saliva population pharmacokinetic (Pop PK) models, as well as summarizes the experiences and ...
Baohua Xu, Yujie Wen, Jinxia Lu, Maobai Liu, Xin Luo, Wei Huang, Helin Xie, Yu Cheng, Hongqiang Qiu, Xuemei Wu   +9 more
wiley   +1 more source

From PICU to NICU: Extrapolating Meropenem Exposure From Pediatric to Neonatal Intensive Care Patients

The Journal of Clinical Pharmacology, EarlyView.
Abstract We previously developed a population pharmacokinetic (PopPK) model for meropenem in pediatric intensive care unit patients accounting for effect of body size, maturation, and kidney function on clearance. This study aimed to extrapolate meropenem exposure to neonates and young infants using the pediatric PopPK model and to validate the ...
Ronaldo Morales Junior, Tomoyuki Mizuno, Wen Rui Tan, Kei Irie, Sonya Tang Girdwood   +4 more
wiley   +1 more source

Grandmother's pregnancy complications and autism spectrum disorders in grandchildren, a California multigenerational cohort study

JCPP Advances, EarlyView.
Abstract Background Pregnancy complications have been associated with offspring autism spectrum disorders (ASD). There has also been increasing evidence for multigenerational risk factors of ASD. Methods In a multigenerational California birth cohort of 1,740,379 mother–child pairs, we investigated pregnancy complications when the grandmother was ...
Ting Chow, Qi Meng, Jingyuan Xiao, Karl O’Sharkey, Zeyan Liew, Beate Ritz   +5 more
wiley   +1 more source

Trends in the incidence of attention deficit hyperactivity disorder in children and early risk factors

JCPP Advances, EarlyView.
Abstract Background Few studies have used nationwide registry data from both primary and secondary healthcare services to examine the incidence of attention‐deficit/hyperactivity disorder (ADHD) in children while accounting for early risk factors. We aimed to investigate trends in ADHD diagnoses and associated risk factors.
Marika Leppänen, Miika Vuori, Bernd Pape, Anniina Kaittila, Siiri‐Liisi Kraav, Tommi Tolmunen, Merja Anis, Max Karukivi, Päivi Rautava   +8 more
wiley   +1 more source

Interhospital variation in the management of Brief Resolved Unexplained Events (BRUE) in infants: A Canadian multicenter cohort study

Journal of Hospital Medicine, EarlyView.
Abstract Background Guidelines on Brief Resolved Unexplained Event (BRUE) only provide recommendations for infants categorized at lower risk. However, most infants fall into the higher‐risk category, leaving management decisions to individual clinicians and contributing to variation in care.
Nassr Nama, Kara Picco, Polina Kyrychenko, Jeffrey N. Bone, Julie Quet, Jessica L. Foulds, Josée Anne Gagnon, Chris Novak, Brigitte Parisien, Matthew Donlan, Ran D. Goldman, Anupam Sehgal, Ronik Kanani, Joanna Holland, Sanjay Mahant, Eric Coon, Joel S. Tieder, Peter J. Gill, The Canadian BRUE Collaboration (C‐BRUE‐C) and the Canadian Paediatric Inpatient Research Network (PIRN)   +18 more
wiley   +1 more source