Results 191 to 200 of about 387,291 (285)

Frontiers in the Economics of Aging [PDF]

David M. Cutler, Ellen Meara
core  

Preventing Adverse Sequelae of Bacterial Vaginosis: A Public Health Program and Research Agenda

Sexually Transmitted Diseases, 2001
E. Koumans, J. Kendrick
semanticscholar   +1 more source

Comparison of Model‐Predicted and Observed Evinacumab Pharmacokinetics and Efficacy in Children Aged < 5 Years With Homozygous Familial Hypercholesterolemia

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Evinacumab, an angiopoietin‐like 3 inhibitor, significantly reduces low‐density lipoprotein cholesterol (LDL‐C) in patients with homozygous familial hypercholesterolemia (HoFH). Herein, we report pharmacokinetic and efficacy analyses of evinacumab in < 5‐year‐old patients with HoFH.
Sébastien Bihorel, Robert Dingman, Jeanne Mendell, Katy C. Norman, Richard T. George, Xue‐Qiao Zhao, Robert Pordy, Daniel Garcia, Wendy S. Putnam, Geetha Raghuveer, Brian W. McCrindle, Elena Fornari, Ivo Baric, Shubha Srinivasan, Melissa Diamond, Eliot A. Brinton, John D. Davis, A. Thomas DiCioccio, Lutz Harnisch   +18 more
wiley   +1 more source

Systematic review and meta-analysis of risk prediction models for retinopathy of prematurity in preterm infants. [PDF]

Biomed Rep
Li L, Gao Y, Chen W, Han M.
europepmc   +1 more source

State‐of‐the‐Art on Model‐Informed Drug Development Approaches for Pediatric Rare Diseases

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Pediatric rare diseases present unique challenges for drug development due to small patient populations, ethical constraints on clinical trial design, and limited prospectively defined natural history data. Model‐Informed Drug Development (MIDD) has emerged as a powerful paradigm to address these challenges by leveraging quantitative methods ...
Rajesh Krishna, Amitava Mitra, Matthew L. Zierhut, Lilly East, Chandra Durairaj   +4 more
wiley   +1 more source

Infant gut microbiome reprogramming following introduction of solid foods (weaning). [PDF]

Gut Microbes
Ding M, Ross RP, Dempsey E, Li B, Stanton C.   +4 more
europepmc   +1 more source

Constraints and Frugal Innovation: Enabling Sustainable Production Through the New Product Development Process

Sustainable Development, EarlyView.
ABSTRACT This paper advances understanding of how constraint‐based thinking fosters sustainable innovation under resource limitations. Based on five case studies of small and medium‐sized enterprises and research groups developing frugal medical devices across diverse regions, it identifies how market, infrastructure, and user constraints shape design ...
Zulfiya Ukbaeva, Theresa Wöllner, Peter M. Bican   +2 more
wiley   +1 more source

Adverse pregnancy outcomes and complications of tuberculosis in pregnant women. [PDF]

Front Cell Infect Microbiol
Su Y, Kong X, Chen Z, Wang X, Lu S.
europepmc   +1 more source

Advancing Tuberculosis Chemotherapy: Targeted Nanomedicines for the Mycobacterium TB Granuloma

Small, EarlyView.
This graphical abstract illustrates nanosystems used for targeted drug delivery into tuberculosis granulomas. It shows how targeting is influenced by size, pH, redox sensitivity, and surface charge. Various nanoparticles are incorporated with drugs to enhance penetration, stability, and release.
Shreya Ranjith Singh, Maya Mellisa Makatini, Thashree Marimuthu, Yahya Essop Choonara   +3 more
wiley   +1 more source

Spontaneous partial chorioamniotic membrane separation followed by the formation of amniotic bands: a case report. [PDF]

BMC Pregnancy Childbirth
Wu S, Tan X, Zhou R.
europepmc   +1 more source