Results 161 to 170 of about 231,985 (288)

Photo Quiz: Unexpected yeast in a premature infant-pathogen or passenger. [PDF]

J Clin Microbiol
Xue YC, Aigbivbalu LO, Holekamp KJ, Ren P.   +3 more
europepmc   +1 more source

New insights into applications of base editor in hereditary disorders

Interdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai, Linhui Zhang, Liqing Li, Yue Liu, Canbin Lv, Yan Shi, Jianyuan Zhao, Dingwei Ye, Yuanyuan Qu   +8 more
wiley   +1 more source

Patent Ductus Arteriosus Occlusion in the Premature Infant: Persistent Research Gaps. [PDF]

J Soc Cardiovasc Angiogr Interv
Ing FF, Backes CH.
europepmc   +1 more source

A Novel Maturation Equation for Hepatic Clearance Across Preterm, Term Neonates, Children, and Adults: Application to Paracetamol and Its Metabolite

The Journal of Clinical Pharmacology, EarlyView.
Abstract A preterm and term neonate to adult (PTNA) maturation equation was introduced recently to describe the glomerular filtration rate maturation from birth to adulthood for neonates of varying gestational age. This study aims to evaluate the newly developed PTNA equation against common maturation approaches like allometric scaling (AS0.75), the ...
Yunjiao Wu, Swantje Völler, Sebastiaan C. Goulooze, Karel Allegaert, Catherine M. T. Sherwin, Anne van Rongen, Daniëlla W. E. Roofthooft, Sinno H. P. Simons, Dick Tibboel, Robert B. Flint, John N. van den Anker, Catherijne A. J. Knibbe   +11 more
wiley   +1 more source

Parenting experiences of informal caregivers of preterm infants during the first 2 years of life at corrected age: a qualitative systematic review protocol. [PDF]

JBI Evid Synth
Srichalerm T, Kankaew S, Kamkhoad D, Saehoong S.   +3 more
europepmc   +1 more source

Saliva as a TDM matrix and its application in the model‐informed precision dosing

The Journal of Clinical Pharmacology, EarlyView.
Abstract This study reviews the main points of saliva as a therapeutic drug monitoring (TDM) matrix, its advantages and limitations, the methods of saliva sample collection and testing, the types of drugs in saliva TDM, and the methods of establishing saliva population pharmacokinetic (Pop PK) models, as well as summarizes the experiences and ...
Baohua Xu, Yujie Wen, Jinxia Lu, Maobai Liu, Xin Luo, Wei Huang, Helin Xie, Yu Cheng, Hongqiang Qiu, Xuemei Wu   +9 more
wiley   +1 more source

An Information App (e-TOP) to Support Parents' Information Needs During the First Year at Home After Preterm Birth: Development and Usability Study. [PDF]

JMIR Pediatr Parent
Flierman M, Möller EL, Vijn VL, Engelbert RH, Jeukens-Visser M, van Kaam AH, Bossen D.   +6 more
europepmc   +1 more source

From PICU to NICU: Extrapolating Meropenem Exposure From Pediatric to Neonatal Intensive Care Patients

The Journal of Clinical Pharmacology, EarlyView.
Abstract We previously developed a population pharmacokinetic (PopPK) model for meropenem in pediatric intensive care unit patients accounting for effect of body size, maturation, and kidney function on clearance. This study aimed to extrapolate meropenem exposure to neonates and young infants using the pediatric PopPK model and to validate the ...
Ronaldo Morales Junior, Tomoyuki Mizuno, Wen Rui Tan, Kei Irie, Sonya Tang Girdwood   +4 more
wiley   +1 more source

Spatial variation in cause-specific premature mortality and its association with socioeconomic deprivation in Belgium from 2000 to 2019. [PDF]

Arch Public Health
Otavova M, Schlüter BS, Faes C, Bouland C, Declercq EM, Vandeninden B, Devleesschauwer B, Masquelier B.   +7 more
europepmc   +1 more source

Prominent Chiari Network as a Cause of Cyanosis in Infants: A Case Report and Implications for Pediatric Cardiology Practice

Journal of Clinical Ultrasound, EarlyView.
A prominent Chiari network can cause cyanosis in infants by inducing a positional right‐to‐left atrial shunt. Accurate diagnosis enabled conservative management, delaying surgery until optimal conditions. This case emphasizes the importance of echocardiographic evaluation in differentiating cyanosis mechanisms to guide appropriate treatment in ...
Carmen Rodríguez‐Barrios, Irene Gutierrez‐Rosa, Moises Rodriguez‐Gonzalez   +2 more
wiley   +1 more source