Results 161 to 170 of about 219,424 (290)

From multi‐omics to precision medicine in intracranial aneurysm: Biomarker discovery and multimodal integration

open access: yesInterdisciplinary Medicine, EarlyView.
This review explores intracranial aneurysm biomarker discovery through multi‐omics. It reveals key genes, proteins, and metabolites, and shows how machine‐learning‐based multi‐modal integration may aid diagnosis and treatment. Abstract Despite extensive research, currently, no biomarkers are available for clinical use in intracranial aneurysm (IA ...
Jiaxin Zhang   +4 more
wiley   +1 more source

A Physiologically Based Modeling Approach to Evaluate Intravenous Levetiracetam Dosing in Term and Preterm Neonates

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Seizures are the most common neurologic emergency in neonates and are associated with significant morbidity and mortality. Current first‐line pharmacotherapy, phenobarbital, is associated with serious adverse effects, including impairment of the developing brain.
Alexis Johnson   +4 more
wiley   +1 more source

Prominent Chiari Network as a Cause of Cyanosis in Infants: A Case Report and Implications for Pediatric Cardiology Practice

open access: yesJournal of Clinical Ultrasound, EarlyView.
A prominent Chiari network can cause cyanosis in infants by inducing a positional right‐to‐left atrial shunt. Accurate diagnosis enabled conservative management, delaying surgery until optimal conditions. This case emphasizes the importance of echocardiographic evaluation in differentiating cyanosis mechanisms to guide appropriate treatment in ...
Carmen Rodríguez‐Barrios   +2 more
wiley   +1 more source

Associations of fetal and infant growth patterns with behavior and cognitive outcomes in early adolescence

open access: yesJCPP Advances, EarlyView.
Abstract Background Fetal life and infancy might be critical periods for brain development leading to increased risks of neurocognitive disorders and psychopathology later in life. We examined the associations of fetal and infant weight growth patterns and birth characteristics with behavior and cognitive outcomes at the age of 13 years.
Romy Gonçalves   +7 more
wiley   +1 more source

Do the early social environment and persistent peripartum depressive symptoms shape toddlers' expressive language?

open access: yesJCPP Advances, EarlyView.
Abstract Background Extensive research suggests that peripartum depression is a risk factor for children's early language development. Yet, previous research on this association shows mixed results, often lacking information on the persistence of depression and the social context.
Hsing‐Fen Tu   +3 more
wiley   +1 more source

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