Results 191 to 200 of about 1,324,038 (335)

Saliva as a TDM matrix and its application in the model‐informed precision dosing

The Journal of Clinical Pharmacology, EarlyView.
Abstract This study reviews the main points of saliva as a therapeutic drug monitoring (TDM) matrix, its advantages and limitations, the methods of saliva sample collection and testing, the types of drugs in saliva TDM, and the methods of establishing saliva population pharmacokinetic (Pop PK) models, as well as summarizes the experiences and ...
Baohua Xu, Yujie Wen, Jinxia Lu, Maobai Liu, Xin Luo, Wei Huang, Helin Xie, Yu Cheng, Hongqiang Qiu, Xuemei Wu   +9 more
wiley   +1 more source

From PICU to NICU: Extrapolating Meropenem Exposure From Pediatric to Neonatal Intensive Care Patients

The Journal of Clinical Pharmacology, EarlyView.
Abstract We previously developed a population pharmacokinetic (PopPK) model for meropenem in pediatric intensive care unit patients accounting for effect of body size, maturation, and kidney function on clearance. This study aimed to extrapolate meropenem exposure to neonates and young infants using the pediatric PopPK model and to validate the ...
Ronaldo Morales Junior, Tomoyuki Mizuno, Wen Rui Tan, Kei Irie, Sonya Tang Girdwood   +4 more
wiley   +1 more source

The Thermoregulatory Effect of Immediate Skin-to-Skin Contact for Preterm Infants: A Systematic Review and Meta-Analysis With Trial Sequential Analysis. [PDF]

Cureus
Albzea W, Alrashidi HF, Alsanea S, Alrakaf D, AlOmani D, Alazemi F.   +5 more
europepmc   +1 more source

Concurrent validity and reliability of the Alberta Infant Motor Scale in premature infants.

Jornal de Pediatria, 2008
K. M. Almeida, M. V. Dutra, R. R. Mello, A. B. Reis, Priscila S. Martins   +4 more
semanticscholar   +1 more source

Prominent Chiari Network as a Cause of Cyanosis in Infants: A Case Report and Implications for Pediatric Cardiology Practice

Journal of Clinical Ultrasound, EarlyView.
A prominent Chiari network can cause cyanosis in infants by inducing a positional right‐to‐left atrial shunt. Accurate diagnosis enabled conservative management, delaying surgery until optimal conditions. This case emphasizes the importance of echocardiographic evaluation in differentiating cyanosis mechanisms to guide appropriate treatment in ...
Carmen Rodríguez‐Barrios, Irene Gutierrez‐Rosa, Moises Rodriguez‐Gonzalez   +2 more
wiley   +1 more source

Challenges and enhancement of health: a dual impact of kangaroo care on parents and infants-systematic review. [PDF]

Mhealth
Yarlagadda H, Sandbulte J, Downs E.
europepmc   +1 more source

Development of the Premature Infant Nose Throat-Model (PrINT-Model)—An Upper Airway Replica of a Premature Neonate for the Study of Aerosol Delivery

Pediatric Research, 2008
S. Minocchieri, J. Burren, M. Bachmann, G. Stern, J. Wildhaber, Stefan Buob, R. Schindel, R. Kraemer, U. Frey, M. Nelle   +9 more
semanticscholar   +1 more source

Associations of fetal and infant growth patterns with behavior and cognitive outcomes in early adolescence

JCPP Advances, EarlyView.
Abstract Background Fetal life and infancy might be critical periods for brain development leading to increased risks of neurocognitive disorders and psychopathology later in life. We examined the associations of fetal and infant weight growth patterns and birth characteristics with behavior and cognitive outcomes at the age of 13 years.
Romy Gonçalves, Romy Gaillard, Kelly K. Ferguson, Sara Sammallahti, Manon H. Hillegers, Eric A. P. Steegers, Hanan El Marroun, Vincent W. V. Jaddoe   +7 more
wiley   +1 more source

Do the early social environment and persistent peripartum depressive symptoms shape toddlers' expressive language?

JCPP Advances, EarlyView.
Abstract Background Extensive research suggests that peripartum depression is a risk factor for children's early language development. Yet, previous research on this association shows mixed results, often lacking information on the persistence of depression and the social context.
Hsing‐Fen Tu, Linda Forssman, Emma Fransson, Alkistis Skalkidou   +3 more
wiley   +1 more source

Genetic and environmental influences on sleep quality, ability to settle, and crying duration in 2‐ and 5‐month‐old infants: A longitudinal twin study

JCPP Advances, EarlyView.
This study found that genetic factors largely influence crying duration and settle ability in infancy, while shared environmental factors primarily affect the number of night wakeups. Etiological influences tended to change from 2 to 5 months, reflecting a highly plastic period in infant brain development and in child‐environment interactions. Abstract
Charlotte Viktorsson, Ashraf Yahia, Mark J. Taylor, Angelica Ronald, Kristiina Tammimies, Terje Falck‐Ytter   +5 more
wiley   +1 more source