Results 81 to 90 of about 93,387 (264)

Pregnancy‐related effect on elexacaftor, tezacaftor and ivacaftor pharmacokinetics in women with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Aim The number of pregnancies among women with cystic fibrosis (wwCF) has steadily increased over the past decade. However, the pharmacokinetics (PK) of elexacaftor–tezacaftor–ivacaftor (ETI) during gestation remains uncharacterized, despite its widespread use in this population.
Paulette Magnas, Naim Bouazza, Frantz Foissac, Saïk Urien, Léo Froelicher‐Bournaud, Gabrielle Lui, Victoria Guillemart, Nicolas Carlier, Jennifer Da Silva, Johanna Fesenbeckh, Reem Kanaan, Isabelle Honoré, Clémence Martin, Jean‐Marc Treluyer, Vassilis Tsatsaris, Pierre‐Régis Burgel, Sihem Benaboud   +16 more
wiley   +1 more source

Codeine toxicity via breast Milk: Can this occur and implications for opiate therapy in children

British Journal of Clinical Pharmacology, EarlyView.
Codeine is commonly used in combination analgesic products. The use of codeine during breastfeeding can rarely be associated with serious adverse effects related to genetic polymorphisms affecting codeine's metabolism and disposition. Clinicians treating infants of breastfeeding mothers should be aware of this rare but potentially serious complication.
Michael Rieder
wiley   +1 more source

Humans are not unique: difficult birth is common in placental mammals

Biological Reviews, EarlyView.
ABSTRACT Human childbirth is widely presumed to be uniquely difficult and dangerous compared to birth in other mammals. Tight fetopelvic proportions can result in obstructed labour and contribute to high rates of maternal and neonatal mortality. Ideas summarised under the ‘obstetrical dilemma’ have contributed to this assumption by explaining difficult
Nicole D. S. Grunstra
wiley   +1 more source

Does Breastfeeding Small for Gestational Age Neonates Promote a Healthier Growth Pattern? A Narrative Review

Children
Background: Small for gestational age neonates represent a population at risk of growth failure or deviant growth patterns and long-term metabolic complications.
Natalia Atzemoglou, Nikolaos P. Tzavellas, Niki Dermitzaki, Maria Baltogianni, Foteini Balomenou, Anastasios Serbis, Vasileios Giapros   +6 more
doaj   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

Biological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater, Adam Dušek, Aleksandra Bartelik, Silvia Mandillo, Elisabetta Golini, Mara Rigamonti, Rasneer Sonia Bains, Hamish Forrest, Marion Rivalan, Melissa Long, Anna Kiryk, Lars Lewejohann, Nuno Henrique Franco   +12 more
wiley   +1 more source

Anatomy of the Soft Palate and Its Role in Upper Airway Function: A Narrative Review

Clinical Anatomy, EarlyView.
ABSTRACT The soft palate is a complex anatomical structure, located at the posterior aspect of the oral and nasal cavities, able to dynamically create valve closure of the nasal and the oral cavities. Its precise movement is critical for speech, swallowing, and respiration. Despite its functional importance, detailed characterization of its constituent
James C. D. Miller, Nikki Mills, Ho‐Fung Chan, Alys R. Clark, S. Ali Mirjalili   +4 more
wiley   +1 more source

Percutaneous Deployment of the Sinus‐SuperFlex‐DS Stent for Hybrid Stage I Palliation in Neonates Weighing ≤ 2.5 kg: A Multicenter Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Hybrid stage I palliation (HS1P) has developed as an alternative to the Norwood stage I palliation for neonates with hypoplastic left heart and related left‐sided obstructive lesions. HS1P is currently used in various clinical settings, such as single ventricle palliation, bridge to decision, bridge to biventricular repair, or ...
Johanna Hummel, Jochen Grohmann, Katarzyna Gendera, Götz Müller, Harald Bertram, Matthias Sigler, Dietmar Schranz, Christian Jux, Markus Khalil   +8 more
wiley   +1 more source

Tuberculosis in pregnancy and adverse neonatal outcomes in two peruvian hospitals

European Journal of Obstetrics & Gynecology and Reproductive Biology: X
Background: According to the World Health Organization, tuberculosis (TB) ranks among the top 10 causes of death worldwide. The significance of TB during pregnancy lies in its symptoms, which can be mistaken for physiological changes associated with ...
Noelia V. Garay-Aguilar, Lizbeth R. Reynoso-Rosales, Anita P. Llamo-Vilcherrez, Carlos J. Toro-Huamanchumo   +3 more
doaj   +1 more source

Changes in Eating Disorder Symptoms in Perinatal US Military Servicewomen

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective The perinatal period is a window of exacerbated vulnerability for eating disorder symptoms. Moreover, US military servicewomen represent a population at increased risk for eating disorder psychopathology relative to civilians.
Katherine A. Thompson, Ruby Schrag, Angelina‐Rose J. Thalheimer, Autumn Mains, Stephanie Rioux, Victoria Thomas, Zoe Sinkford, David A. Klein, Mark Haigney, Marian Tanofsky‐Kraff, Jason M. Lavender   +10 more
wiley   +1 more source

COMPARISON OF PLGF LEVELS, AMONG SMALL FOR GESTATIONAL AGE AND APPROPRIATE FOR GESTATIONAL AGE MOTHERS

Pakistan Armed Forces Medical Journal
Objective. Early detection of small for gestational age fetuses can prevent infant morbidity and mortality. The objective of this study was to compare the levels of Placental Growth Factor among small for gestational age with appropriate for gestational
Maryum Imran, Mudassar Sajjad, Talat Shahzad   +2 more
doaj   +1 more source