Results 221 to 230 of about 16,178,120 (306)

Model‐Informed Dose Optimization of Anakinra in Preterm Neonates Implications for Safe and Effective Dosing

Clinical Pharmacology &Therapeutics, EarlyView.
Anakinra, an interleukin‐1 receptor antagonist, shows promise for reducing inflammatory complications of premature birth. However, the pharmacokinetics (PK) of anakinra in neonates has not been characterized, limiting evidence‐based dosing. This study aimed to develop a population PK model for anakinra to guide dosing in preterm neonates.
Jia Li, David K. Metz, Elys Green, Gergely Toldi, Robert Galinsky, Megan Clark, Rebecka Atkinson, Ina Rudloff, Josephine C. Owen, Sara K. DiSimone, Samuel C. Forster, Steven X. Cho, Atif Majid, Graeme R. Polglase, Marcel Favilla, Pramod Pharande, Atul Malhotra, Calum T. Roberts, Scott H. Stansfield, Arvind Sehgal, Kenneth Tan, Alistair J. Gunn, Philip J. Berger, Alex Veldman, Rod W. Hunt, Claudia A. Nold‐Petry, Marcel F. Nold, Carl M. J. Kirkpatrick   +27 more
wiley   +1 more source

Advancing Pregnancy and Pediatric Science through the NIH Transporter Elucidation Network

Clinical Pharmacology &Therapeutics, EarlyView.
Human gestation is characterized by dynamic changes in maternal physiology and maturation of tissue functions before and after birth. The fetus and neonate are highly dependent upon transfer of maternal nutrients via the placenta and lactating mammary gland, which frequently involve selective membrane transporter proteins.
Joanne Wang, Jashvant D Unadkat, Samuel LM Arnold, John K Fallon, Pouria Fattahi, Dan Dongeun Huh, Nicholas Ieronimakis, Edward J Kelly, Svetlana Lutsenko, Robert M Stroud, Jacqueline B Tiley, Jia Yang, Xujia Zhou, Hao Zhu, Rajini Rao, Kathleen M Giacomini, Lauren M Aleksunes   +16 more
wiley   +1 more source

Case Report: Usefulness of transcutaneous bilirubin measurement for the early detection of severe hyperbilirubinemia due to late-onset hemolysis in an extremely low birth weight infant. [PDF]

Front Pediatr
Tanaka K, Utsunomiya T, Nakayama K, Tsuneishi K, Koda T, Okuda M, Takeshima Y.   +6 more
europepmc   +1 more source

Medication Use During Breastfeeding—An Understudied Population: A Five‐Year Experience in the Pharmacovigilance Center of Lyon

Clinical Pharmacology &Therapeutics, EarlyView.
Medication use during breastfeeding is common, yet data on drug transfer into breast milk and infant exposure remain limited. This study describes real‐world requests concerning medication compatibility with breastfeeding managed by the Lyon pharmacovigilance center over five years.
Blandine Bertin, Aurore Gouraud, Anthony Facile, Fanny Ledys, Sabrina Pierre, Véronique Pizzoglio, Thierry Vial, Marine Auffret, Marina Atzenhoffer   +8 more
wiley   +1 more source

Racially motivated hate crime exposure and birth outcomes: Analysis of US vital statistics data 1995-2020. [PDF]

Soc Sci Med
Jiang Y, Rauscher E.
europepmc   +1 more source

Finding My Path: Listening, Learning, and Leading in Rare Disease: The 2025 Hower Award

Annals of the Child Neurology Society, EarlyView.
Andrea Gropman
wiley   +1 more source

Mapping the Intellectual Structure of AI‐Driven ESG Cost Modeling: A Bibliometric Analysis of Trends, Themes, and Future Directions

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The bibliometric and qualitative analyses of 470 publications in the Web of Science Core Collection from 2004 through 2025 in this study associated the intellectual structure and thematic evolution of AI‐driven ESG cost modeling. The research commences using an integrated analytical framework consisting of three tools: (1) Bibliometrix (R) for
Nesreen Al‐Malkawi, Adriana Giret
wiley   +1 more source

Implementation of a Multidisciplinary Transitional Home Care Program for Very-Low-Birth-Weight Infants: A Structured Program Evaluation. [PDF]

Healthcare (Basel)
Hung CW, Wu LM.
europepmc   +1 more source

The ESG Readiness Index Based on Lewin's Field Theory: The Case of the Czech Industrial Sector

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The Corporate Sustainability Reporting Directive (CSRD) imposes comprehensive ESG data requirements, yet the literature predominantly evaluates ex‐post reporting quality rather than ex‐ante organizational readiness. Drawing on Kurt Lewin's Field Theory, this study develops and pilot‐tests an expert‐weighted ESG Readiness Index (ESGRI ...
Vojtěch Hlinák, Barbora Stieberová, Jaroslava Blažková, Miroslav Žilka, Theodor Beran, Jan Lhota   +5 more
wiley   +1 more source

Constructing a predictive model for the risk of periventricular leukomalacia in very low birth weight premature infants based on Lasso-Logistic regression analysis. [PDF]

Front Pediatr
Duan F, Ling L, Liao L.
europepmc   +1 more source