Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez +10 more
wiley +1 more source
Caffeine for apnea of prematurity and brain development at 11 years of age
Objective Caffeine therapy for apnea of prematurity has been reported to improve brain white matter microstructure at term‐equivalent age, but its long‐term effects are unknown. This study aimed to investigate whether caffeine affects (1) brain structure
Claire E. Kelly +9 more
doaj +1 more source
DESIGN OF A SURVEILLANCE SYSTEM FOR PREGNANCY AND ITS OUTCOMES IN RURAL NEPAL
Introduction Community trials in low-income countries require monitoring and evaluation systems. The requirements of a community surveillance system include coherent design, training, field supervision and reporting, as well as the need for a robust and ...
David Osrin +7 more
doaj +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
Infant Mortality in the United States: Provisional Data From the 2023 Period Linked Birth/Infant Death File [PDF]
This report presents provisional 2023 data on infant mortality rates using the U.S. linked birth/infant death files. Infant mortality rates are shown by infant age at death, maternal race and Hispanic origin, maternal age, gestational age, sex of the ...
core
BLASTOMYCOSIS IN AN INFANT. [PDF]
This is a peculiar disease, from a geographic standpoint. Its home so far seems to be confined to America, and only in a few localities, largely in the Mississippi valley, if we also include the city of Chicago. The forms on the Pacific coast seem to differ from those found in other localities in the United States and are named protozoic and ...
openaire +2 more sources
White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian +8 more
wiley +1 more source
A Study Report On Infant Feeding Practices In The Context Of\ud HIV / AIDS [PDF]
\ud \ud This report presents the findings of a study on infant feeding practices in the context of HIV/AIDS in Tanzania. The study was undertaken from 8th – 24th August 2004 in 3 regions implementing PMTCT activities namely Kagera, Mbeya and Kilimanjaro.
Tanzania Food and Nutrition Centre , (TFNC)
core
INFANT TEMPERAMENT AND PARENTING STRESS: RELATION TO MATERNAL AND PATERNAL REFLECTIVE FUNCTION [PDF]
Introduction: Temperament is a basic disposition that differentiates individuals in terms of reactivity and regulation, and it is the result of complex interactions among genetic, biological, and environmental variables across time.
Cristina Sechi +3 more
core
Histopathological Evidence of Neurodegenerative Pathology in Epilepsy: A Systematic Review
ABSTRACT Epilepsy affects > 50 million people worldwide and is associated with a disproportionate burden of cognitive impairment. Emerging evidence suggests that neurodegenerative proteinopathies, particularly hyperphosphorylated tau (p‐tau) and amyloid‐β (Aβ), may contribute to cognitive dysfunction in people with epilepsy (PWE), even in the absence ...
Syeda Amrah Hashmi +7 more
wiley +1 more source

