Results 21 to 30 of about 929,207 (247)

Case Report: Electroencephalography in a neonate with isolated sulfite oxidase deficiency – a case report and literature review [version 1; peer review: 2 approved]

HRB Open Research, 2021
Isolated sulfite oxidase deficiency (ISOD) is a rare autosomal recessive neuro-metabolic disorder caused by a mutation in the sulfite oxidase (SUOX) gene situated on chromosome 12. Due to the deficiency of this mitochondrial enzyme (sulfite oxidase), the
Niamh McSweeney, Brian McNamara, Geraldine B Boylan, Carol M Stephens, Andreea M Pavel, Brian H Walsh, Sean R Mathieson   +6 more
doaj   +1 more source

Tracking regional brain growth up to age 13 in children born term and very preterm

Nature Communications, 2020
In this longitudinal study, the authors tracked the course of brain development from birth to adolescence (age 13 years) and examined the effects of very preterm birth.
Deanne K. Thompson, Lillian G. Matthews, Bonnie Alexander, Katherine J. Lee, Claire E. Kelly, Chris L. Adamson, Rod W. Hunt, Jeanie L. Y. Cheong, Megan Spencer-Smith, Jeffrey J. Neil, Marc L. Seal, Terrie E. Inder, Lex W. Doyle, Peter J. Anderson   +13 more
doaj   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Experiences in running a complex electronic data capture system using mobile phones in a large-scale population trial in southern Nepal

Global Health Action, 2017
The increasing availability and capabilities of mobile phones make them a feasible means of data collection. Electronic Data Capture (EDC) systems have been used widely for public health monitoring and surveillance activities, but documentation of their ...
Sarah Style, B. James Beard, Helen Harris-Fry, Aman Sengupta, Sonali Jha, Bhim P. Shrestha, Anjana Rai, Vikas Paudel, Meelan Thondoo, Anni-Maria Pulkki-Brannstrom, Jolene Skordis-Worrall, Dharma S. Manandhar, Anthony Costello, Naomi M. Saville   +13 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Preparation of spinel ferrites-based flexible electrodes for high electrochemical performances

Chemical Physics Impact
In this study, we synthesized two different types of spinel ferrites as CoFe2O4 and NiFe2O4 nanocomposites by thermal decomposition method to improve the performance of supercapacitor research. Numerous physicochemical characterization tests, including X-
Infant Francita Fonseka Christopher, Amudhavalli Karuppiah   +1 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Cost of illness due to respiratory syncytial virus acute lower respiratory tract infection among infants hospitalized in Argentina

BMC Public Health
Background Information is scarce regarding the economic burden of respiratory syncytial virus (RSV) disease in low-resource settings. This study aimed to estimate the cost per episode of hospital admissions due to RSV severe disease in Argentina. Methods
Julia Dvorkin, Emiliano Sosa, Elizabeth Vodicka, Ranju Baral, Andrea Sancilio, Karina Dueñas, Andrea Rodriguez, Carlos Rojas-Roque, Patricia B. Carruitero, Fernando P. Polack, Clint Pecenka, Romina Libster, Mauricio T. Caballero   +12 more
doaj   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source