Results 101 to 110 of about 865,721 (297)

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +3 more
wiley   +1 more source

Common gastrointestinal symptoms in healthy infants receiving goat milk-based formula or cow’s milk-based formula: a double-blind, randomized, controlled trial

BMC Pediatrics
Objective To assess common gastrointestinal symptoms in healthy Brazilian infants receiving goat milk-based formula (GMF) compared to cow’s milk-based formula (CMF).
P. Maximino, L. van Lee, Yvonne N. Meijer-Krommenhoek, L. van der Zee, H. da Costa Ribeiro Junior   +4 more
doaj   +1 more source

Advertisements of follow-on formula and their perception by pregnant women and mothers in Italy

, 2015
Objective To assess how follow-on formula milks for infants aged 6–12 months are presented to and understood by mothers. Design A quantitative and qualitative cross-sectional study including (1) an analysis of advertisements in three magazines for ...
Mutti, Valentina, Group, Alessandra Knowles1 on behalf of the Follow on Formula Research, Pani, Paola, Cattaneo, Adriano, Guidetti, Cecilia, Carletti, Claudia, GUIDETTI, MARGHERITA   +6 more
core   +1 more source

Extrapolation and pharmacokinetic protocol design optimization for ceftriaxone as an exemplar for the development of antibiotics for children

British Journal of Clinical Pharmacology, EarlyView.
Aim Ceftriaxone is a cephalosporin commonly used for the treatment of acute, severe infections; however, there are conflicting data on its disposition properties in children, making it a suitable case study for the evaluation of the appropriateness of extrapolation approaches based on exposure matching principles for paediatric patients and exploring ...
Daniel Valente Neves, Umberto Villani, Salvatore D'Agate, Sean Oosterholt, Ricardo de Carvalho Cavalli, Fabio Carmona, Vera Lucia Lanchote, Oscar Della Pasqua   +7 more
wiley   +1 more source

Plasma and breast milk pharmacokinetics of suvorexant in healthy lactating women

British Journal of Clinical Pharmacology, EarlyView.
Aim This paper aims to evaluate the plasma and breast milk pharmacokinetics of suvorexant, an orexin receptor antagonist used to treat insomnia at a maximum dose of 20 mg, in healthy lactating women. Methods The paper reports on an open‐label Phase 1 study in 12 healthy lactating women.
Jacqueline McCrea, Andrew Litovsky, Prachi Wickremasingha, Nairita Ghosal, Brad Roadcap, Robert Valesky, Robin Lee, Leea D. Reed, Ming Wang, Wei Fang, Rebecca Wrishko   +10 more
wiley   +1 more source

Infant Feeding Practices and Their Association with Early-Life Nutrient Intake: Baseline Findings from the Baby-Act Trial

Dietetics
Introduction: This is a secondary cross-sectional analysis of participants’ baseline data from the Baby-Act Trial to compare energy and macronutrients intake by feeding type.
Cristina Palacios, Elvira Alvarez, Maria Gabriela Kallis, Yari Valle, Jeremy Pomeroy, Maribel Campos   +5 more
doaj   +1 more source

Infant formula powders

, 2013
Human milk is the best food for all human infants. However, there are situations where the mother cannot or does not want to breastfeed. In such situations, an alternative food is necessary: an infant formula. The aim of infant formulae is thus to try to
E. Blanchard, P. Schuck, Blanchard, Eric, Zhu, Peng, Schuck, Pierre, P. Zhu   +5 more
core   +1 more source

Entrepreneurial Orientation and Supply Chain Sustainability: A Systematic Literature Review

Business Strategy and the Environment, EarlyView.
ABSTRACT In increasingly volatile global markets, firms must cultivate entrepreneurial and adaptive capabilities to sustain competitiveness and advance sustainability objectives. This study systematically reviews the intersection of Entrepreneurial Orientation (EO), Supply Chain Management (SCM) practices, and sustainability performance through the ...
Olivia Finnerty, Graham Heaslip, Simon Stephens, Roisin Lyons, George Onofrei   +4 more
wiley   +1 more source

Governments Push Infant Formula

World Nutrition, 2019
Mélissa Mialon
doaj   +1 more source