Results 131 to 140 of about 461,229 (347)

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

Spatial Modeling of Infant Mortality Rate In Sampang Regency : An Ecological Study

open access: yesJournal of Applied Geospatial Information
Infant mortality rate (IMR) is one of the indicators to measure public health status and community welfare. In the last 3 years (2014-2016), the infant mortality rate in Sampang Regency has increased. The purpose of this study is to develop spatial-based
Firman Firdauz Saputra   +6 more
doaj   +1 more source

Average age at death in infancy and infant mortality level: reconsidering the Coale-Demeny formulas at current levels of low mortality [PDF]

open access: yes
The longterm historical decline in infant mortality has been accompanied by increasing concentration of infant deaths at the earliest stages of infancy.
Evgueni M. Andreev, W. Ward Kingkade
core  

The correlates of infant and childhood mortality [PDF]

open access: yes
This paper has two main goals. The first is to review the context for studying infant mortality, which includes a review of the theoretical framework, the covariates used to examine mortality over the first 60 months of life, and the major findings of ...
Krzysztof Tymicki
core  

Pulmonary congestion relief by adding dapagliflozin to intravenous loop diuretic in acute heart failure patients

open access: yesESC Heart Failure, EarlyView.
Abstract Aims We aim to assess the efficacy of congestion relief and safety associated with adding SGLT2i (viz., dapagliflozin 10 mg) to intravenous loop diuretics within 24 h of hospital presentation in patients with acute heart failure (AHF). Methods and results A single‐centre open‐label clinical research study enrolled 98 patients admitted with an ...
Daniela Mocan   +7 more
wiley   +1 more source

Infant and child mortality in Afghanistan: A scoping review

open access: yesHealth Science Reports
Background and Aims Since 1990, global child and infant mortality rates have typically stabilized or decreased due to improved healthcare, vaccination rollouts, and international funding.
Khulud Qamar   +5 more
doaj   +1 more source

Infant Mortality and the Health of Survivors: Britain 1910-1950 [PDF]

open access: yes
The first half of the twentieth century saw rapid improvements in the health and height of British children. Average height and health can be related to infant mortality through a positive selection effect and a negative scarring effect.
Hatton, Timothy J.
core  

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons   +17 more
wiley   +1 more source

Seminars in epileptology: How to diagnose status epilepticus in adults and children

open access: yesEpileptic Disorders, EarlyView.
Abstract Status epilepticus (SE) can be regarded as the most severe expression of seizure activity characterized by a low probability of spontaneous cessation and mechanisms leading to metabolic and inflammatory derangements with increased risk of brain damage, alterations of neural networks, and potentially life‐threatening systemic complications ...
M. Leitinger   +12 more
wiley   +1 more source

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