Results 301 to 310 of about 3,070,666 (388)

Intersecting ethnic and socioeconomic inequalities in infant mortality in England, 2007-2019. [PDF]

open access: yesArch Dis Child
Esan OB   +6 more
europepmc   +1 more source

Ultra‐Sensitive Quantification of Indoxyl Sulfate and 3‐Carboxy‐4‐Methyl‐5‐Propyl‐2‐Furanpropanoic Acid in Plasma Using Ultra‐Performance Liquid Chromatography Coupled to Quadrupole Time‐of‐Flight Mass Spectrometry

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
We established and validated a novel ultra‐sensitive method for simultaneous quantification of uremic toxins using ultra‐performance liquid chromatography coupled to quadrupole time‐of‐flight mass spectrometry. This assay met the acceptance criteria of the U.S. Food and Drug Administration bioanalytical method validation guidance.
Jun Negami   +10 more
wiley   +1 more source

A Retrospective Analysis of PK and Response of Oral Ibuprofen in the Treatment of a Patent Ductus Arteriosus in Extremely Low Gestational Age Neonates

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Oral ibuprofen is the preferred pharmacotherapeutic option for treatment of a persistent patent ductus arteriosus (PDA), but evidence for its optimal use in extremely low gestational age newborns (ELGANs) remains limited. In the current study, we aimed to investigate the pharmacokinetics and exposure‐response relationship of oral ibuprofen in ...
Mohd Asif   +6 more
wiley   +1 more source

A Physiologically Based Modeling Approach to Evaluate Intravenous Levetiracetam Dosing in Term and Preterm Neonates

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Seizures are the most common neurologic emergency in neonates and are associated with significant morbidity and mortality. Current first‐line pharmacotherapy, phenobarbital, is associated with serious adverse effects, including impairment of the developing brain.
Alexis Johnson   +4 more
wiley   +1 more source

From PICU to NICU: Extrapolating Meropenem Exposure From Pediatric to Neonatal Intensive Care Patients

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract We previously developed a population pharmacokinetic (PopPK) model for meropenem in pediatric intensive care unit patients accounting for effect of body size, maturation, and kidney function on clearance. This study aimed to extrapolate meropenem exposure to neonates and young infants using the pediatric PopPK model and to validate the ...
Ronaldo Morales Junior   +4 more
wiley   +1 more source

Klippel‐Trénaunay‐Weber Syndrome: Prenatal Diagnosis and Review of the Literature

open access: yesJournal of Clinical Ultrasound, Volume 53, Issue 3, Page 535-546, March/April 2025.
This meta‐analysis demonstrates the high diagnostic accuracy of SZ‐CEUS for differentiating between malignant and benign focal liver lesions, as well as for HCC from non‐HCC lesions. The study shows better performance for smaller lesions and those with a higher proportion of malignancy.
Giuliana Orlandi   +13 more
wiley   +1 more source

A new birth weight chart and optimal birth weight percentiles for predicting infant mortality. [PDF]

open access: yesSci Rep
Chang JC   +7 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy