Results 31 to 40 of about 47,738 (314)

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Is malnutrition declining? An analysis of changes in levels of child malnutrition since 1980

Bulletin of the World Health Organization
Nutritional status is the best global indicator of well-being in children. Although many surveys of children have been conducted since the 1970s, lack of comparability between them has made it difficult to monitor trends in child malnutrition.
Mercedes de Onis, Edward A. Frongillo, Monika Blössner   +2 more
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Nutrition Country Profile United Republic of Tanzania [PDF]

, 2008
Population, Economic, Tanzania, urbanization ...
Kinabo, Joyce, Palma, Giulia, Bader, Estelle   +2 more
core  

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

The Influence of Maternal Prenatal and Early Childhood Nutrition and Maternal Prenatal Stress on Offspring Immune System Development and Neurodevelopmental Disorders

Frontiers in Neuroscience, 2013
The developing immune system and central nervous system in the fetus and child are extremely sensitive to both exogenous and endogenous signals. Early immune system programming, leading to changes that can persist over the life course, has been ...
Andrea Horvath Marques, Andrea Horvath Marques, Thomas G O'Connor, Christine eRoth, Christine eRoth, Ezra eSusser, Ezra eSusser, Ezra eSusser, Anne-Lise eBjørke-Monsen   +8 more
doaj   +1 more source

Feeding behaviour and its relationship to weight gain in infancy: behaviour and its relationship to weight gain [PDF]

, 1997
This thesis involved a longitudinal study of 30 healthy infants from 6 weeks to 15 months to investigate the relationship between feeding behaviour and weight gain in infancy. Poor infant weight gain is associated with adverse outcomes in childhood (e.g.
Young, Bridget
core  

HIV status, breastfeeding modality at 5 months and postpartum maternal weight changes over 24 months in rural South Africa [PDF]

, 2014
Objective: To determine the effect of infant feeding practices on postpartum weight change among HIV-infected and -uninfected women in South Africa.<p></p> Methods: In a non-randomised intervention cohort study of antiretroviral therapy ...
Newell, Marie-Louise, Chetty, Terusha, Bland, Ruth M., Carter, Rosalind J.   +3 more
core   +1 more source

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

Advanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

Advantages of breastfeeding for the mother-infant dyad

Journal of Health Inequalities
Breastfeeding is considered to be the best and optimal mode of infant feeding, providing health benefits for both the child and the mother. Maternal milk contains all the necessary nutrients, strengthens the baby’s immune system, reduces the risk of ...
Zuzanna Chęcińska-Maciejewska, Andrzej Ciborek, Hanna Krauss, Magdalena Gibas-Dorna   +3 more
doaj   +1 more source