Results 21 to 30 of about 3,364,693 (178)

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

The effects of maternal and infant vitamin A supplementation on vitamin A status: a randomised trial in Kenya. [PDF]

, 2007
Postpartum vitamin A supplementation of mothers and infants is recommended, but the efficacy has been questioned. In this double-blind, placebo-controlled trial, Kenyan mother-infant pairs were randomised to maternal vitamin A (400,000 IU) or placebo 0 ...
D. L. Mwaniki, Marshall, T, Tedstone, A.E., Alusala, D., Luoba, A, Ayah, R.A., Magnussen, Pascal, Tedstone, AE, D. Alusala, Michaelsen, KF, Michaelsen, Kim Fleischer, Friis, H, Mwaniki, DL, Luoba, A., K. F. Michaelsen, P. Kaestel, Magnussen, P, A. Luoba, Alusala, D, R. A. Ayah, A. E. Tedstone, Friis, Henrik, Kaestel, P, Marshall, T., P. Magnussen, Ayah, RA, H. Friis, Mwaniki, D.L., T. Marshall, Kæstel, Pernille   +29 more
core   +1 more source

The natural history of periodontal disease—Part 2: In populations with access to dental care: The Studies of Health in Pomerania (SHIP)

Periodontology 2000, EarlyView., 2023
Abstract In this descriptive analysis of the 21‐year follow‐up data from the SHIP‐START cohort and the 7‐year follow‐up data from the SHIP‐TREND cohort, we report the progression of clinical attachment levels (CAL), age effects on CAL change, and a detailed description of CAL progression and remission. At baseline, 4307 and 4420 persons participated in
Thomas Kocher, Peter Meisel, Reiner Biffar, Henry Völzke, Birte Holtfreter   +4 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Advancing Pregnancy and Pediatric Science through the NIH Transporter Elucidation Network [PDF]

Clin Pharmacol Ther
Human gestation is characterized by dynamic changes in maternal physiology and maturation of tissue functions before and after birth. The fetus and neonate are highly dependent upon transfer of maternal nutrients via the placenta and lactating mammary gland, which frequently involve selective membrane transporter proteins.
Wang J, Unadkat J, Arnold S, Fallon J, Fattahi P, Huh D, Ieronimakis N, Kelly E, Lutsenko S, Stroud R, Tiley J, Yang J, Zhou X, Zhu H, Rao R, Giacomini K, Aleksunes L.   +16 more
europepmc   +2 more sources

Recent Advances in High‐Entropy Nanozymes: From Fabrication to Applications

Advanced Science, EarlyView.
To highlight key achievements and clarify the current landscape of high‐entropy nanozymes (HEAzymes), this review summarizes state‐of‐the‐art developments ranging from thermodynamically and kinetically controlled synthetic strategies; enzyme‐like catalytic types, catalytic characteristics, and underlying mechanisms; to their antioxidative, therapeutic,
Yongjian Ai, Weibo Zhang, Pengjie Wang, Wentao Xu, Huiyuan Guo, Hong‐bin Sun, Meng‐Qi He, Fazheng Ren, Qionglin Liang   +8 more
wiley   +1 more source

Nested Selves: Self‐Organization and Shared Markov Blankets in Prenatal Development in Humans

Topics in Cognitive Science, EarlyView., 2023
Abstract The immune system is a central component of organismic function in humans. This paper addresses self‐organization of biological systems in relation to—and nested within—other biological systems in pregnancy. Pregnancy constitutes a fundamental state for human embodiment and a key step in the evolution and conservation of our species. While not
Anna Ciaunica, Michael Levin, Fernando E. Rosas, Karl Friston   +3 more
wiley   +1 more source

The global extent of polypharmacy in neonatal intensive care: A systematic review

British Journal of Clinical Pharmacology, EarlyView.
Aims Pharmaceutical treatment in the neonatal intensive care unit (NICU) is challenging, with neonates often receiving multiple drugs during hospitalization. Given their physiological immaturity, polypharmacy raises concerns about potential adverse effects, drug–drug interactions and the risk of supratherapeutic or subtherapeutic treatment.
Mia Finserås Bretun, Ditte Resendal Gotfredsen, Aase Merethe Raddum, Charlotte Vermehren, Jón Þór Trærup Andersen, Ulrik Lausten‐Thomsen, Christina Gade   +6 more
wiley   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Are Homemade and Commercial Infant Foods Different? A Nutritional Profile and Food Variety Analysis in Spain

, 2021
Complementary feeding (CF) is an important determinant of early and later life nutrition with great implications for the health status and the development of an adequate growth.
Maria Jose Bernal, Michelle Klerks, Roman, Juan Francisco Haro-Vicente, Luis Manuel Sanchez-Siles, Sergio Roman   +5 more
core   +1 more source