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Hypoxia-Induced Cyr61/CCN1 Production in Infantile Hemangioma

Plastic and Reconstructive Surgery, 2021
Supplemental Digital Content is available in the text. Background: Hypoxia may play a role in the pathogenesis of infantile hemangioma. Cysteine-rich angiogenic inducer 61 (Cyr61), or CCN1, can be induced under hypoxic conditions in several types of ...
Pinru Wu   +6 more
semanticscholar   +1 more source

Infantile Hemangiomas

American Journal of Clinical Dermatology, 2013
Infantile hemangioma (IH) is a common vascular tumor of infancy. Although benign, infants with IH can experience complications including ulceration, visual and airway impairment, and residual scarring and disfigurement. It is often challenging for clinicians to predict which tumors are in need of systemic treatment.
Beth A. Drolet   +2 more
openaire   +3 more sources

Treatment of Infantile Hemangiomas

Pediatric Annals, 2012
CME Educational Objectives 1. Recognize infantile hemangiomas that are associated with a higher risk for complications and associated anomalies. 2.
Christine T. Lauren, Maria C. Garzon
openaire   +3 more sources

Infantile Hemangioma: A Current Review.

Journal of pediatric hematology/oncology, 2021
Infantile hemangiomas (IHs) are common vascular lesions which are benign but can cause significant functional and cosmetic morbidity. Since the fortuitous discovery of propranolol being effective to treat IH over a decade ago, the therapy and prognosis ...
Kristy S. Pahl, T. McLean
semanticscholar   +1 more source

Is prolonged monitoring necessary? An updated approach to infantile hemangioma treatment with oral propranolol

Pediatric dermatology, 2021
Infantile hemangiomas (IH) are the most common soft‐tissue tumors in childhood, occurring in up to 1 in 10 infants. Oral propranolol has been well established as the first‐line treatment of complicated hemangiomas; however, variability in the ...
M. Johansen, Geetha Mahendran, L. Lawley
semanticscholar   +1 more source

Pathogenesis of Infantile Hemangioma

Facial Plastic Surgery, 2012
Cutaneous vascular anomalies are congenital disorders of abnormal vascular development and growth. Infantile hemangioma is a common type of vascular anomalies characterized by the abnormal growth of blood vessels in the early proliferative phase, followed by the gradual spontaneous regression of the lesion in the involuting phase. Over the past decade,
Marcelo Hochman, Thuy L. Phung
openaire   +3 more sources

Update on infantile hemangiomas

Seminars in Perinatology, 2013
Infantile hemangiomas are the most common tumors of infancy. The serendipitous discovery of the therapeutic efficacy of propranolol in the management of infantile hemangiomas has revolutionized the care and understanding of these lesions, and greatly improved the prognosis for a good cosmetic outcome.
Kachiu C. Lee   +2 more
openaire   +3 more sources

β-blocker therapy for infantile hemangioma

Expert Review of Clinical Pharmacology, 2020
Introduction Fifteen percent of proliferating infantile hemangioma (IH) require intervention because of the threat to function or life, ulceration, or tissue distortion. Propranolol is the mainstay treatment for problematic proliferating IH.
S. P. Koh   +3 more
semanticscholar   +1 more source

Pathogenesis of Infantile Hemangiomas

Pediatric Annals, 2012
CME Educational Objectives 1. Review the key features of the life cycle of infantile hemangiomas. 2. Highlight cellular and molecular pathways involved in hemangioma-genesis.
Lily Changchien Uihlein   +2 more
openaire   +3 more sources

Mimickers of Infantile Hemangiomas

Pediatric Dermatology, 2017
AbstractInfantile hemangiomas (IHs) are the most common tumors of infancy and usually follow a typical course of growth and involution. We report four soft tissue tumors that were referred to the pediatric dermatology clinic as IHs and the process by which they were diagnosed and treated.
Ross M. Brockman   +7 more
openaire   +3 more sources

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