Results 1 to 10 of about 2,594,965 (393)

Bivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in Infants.

New England Journal of Medicine, 2023
BACKGROUND Whether vaccination during pregnancy could reduce the burden of respiratory syncytial virus (RSV)-associated lower respiratory tract illness in newborns and infants is uncertain.
B. Kampmann, S. Madhi, I. Munjal, E. Simões, B. Pahud, C. Llapur, J. Baker, Gonzalo Pérez Marc, D. Radley, Emma Shittu, Julia R Glanternik, Hasra Snaggs, James Baber, Philip Zachariah, S. Barnabas, Merlin Fausett, Tyler Adam, Nicole Perreras, M. V. van Houten, A. Kantele, Li-Min Huang, Louis J. Bont, Takeo Otsuki, Sergio L Vargas, Joanna Gullam, B. Tapiéro, R. Stein, F. Polack, H. Zar, N. B. Staerke, María Duron Padilla, Peter C. Richmond, K. Koury, Katherine Schneider, E. V. Kalinina, David Cooper, K. Jansen, A. Anderson, K. Swanson, W. Gruber, A. Gurtman   +40 more
semanticscholar   +1 more source

Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants.

New England Journal of Medicine, 2022
BACKGROUND Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infection and hospitalization in infants. Nirsevimab is a monoclonal antibody to the RSV fusion protein that has an extended half-life.
L. Hammitt, R. Dagan, Yuan Yuan, M. Baca Cots, M. Bosheva, S. Madhi, W. Muller, H. Zar, Dennis Brooks, Amy Grenham, U. Wählby Hamrén, V. S. Mankad, P. Ren, Therese Takas, M. Abram, A. Leach, M. P. Griffin, T. Villafana   +17 more
semanticscholar   +1 more source

Mortality, In-Hospital Morbidity, Care Practices, and 2-Year Outcomes for Extremely Preterm Infants in the US, 2013-2018.

Journal of the American Medical Association (JAMA), 2022
Importance Despite improvement during recent decades, extremely preterm infants continue to contribute disproportionately to neonatal mortality and childhood morbidity.
E. Bell, S. Hintz, N. Hansen, C. Bann, M. Wyckoff, S. Demauro, M. Walsh, B. Vohr, B. Stoll, W. Carlo, K. V. van Meurs, M. Rysavy, R. Patel, S. Merhar, P. Sánchez, A. Laptook, A. Hibbs, C. Cotten, C. D'Angio, Sarah Winter, J. Fuller, Abhik Das   +21 more
semanticscholar   +1 more source

Protein interaction networks define the genetic architecture of preterm birth

Scientific Reports, 2022
The likely genetic architecture of complex diseases is that subgroups of patients share variants in genes in specific networks sufficient to express a shared phenotype.
Alper Uzun, Jessica S. Schuster, Joan Stabila, Valeria Zarate, George A. Tollefson, Anthony Agudelo, Prachi Kothiyal, Wendy S. W. Wong, James Padbury   +8 more
doaj   +1 more source

A self-efficacy-enhancing physical activity intervention in women with high-risk factors for gestational diabetes mellitus: study protocol for a randomized clinical trial

Trials, 2022
Background Gestational diabetes mellitus (GDM) is one of the most common medical disorders in pregnancy. Evidence has demonstrated that moderate-intensity physical activity may reduce the risk of gestational diabetes.
Xiao Yang, Ji Zhang, Xiangzhi Wang, Yi Xu, Li Sun, Yingli Song, Ruijuan Bai, Hui Huang, Jing Zhang, Ruixing Zhang, Erfeng Guo, Lingling Gao   +11 more
doaj   +1 more source

Asthma and Vitamin D Deficiency: Occurrence, Immune Mechanisms, and New Perspectives

Journal of Immunology Research, 2022
Asthma, as a chronic inflammatory condition of the airways, has a considerable prevalence among children. Vitamin D might play a role in asthma pathogenesis by affecting the development of the lung, regulating the immune responses, and remodeling of ...
Fardis Salmanpour, Naghmeh Kian, Noosha Samieefar, Mohammad Amin Khazeei Tabari, Nima Rezaei   +4 more
doaj   +1 more source

Heterotopic Pregnancy: Case Series and Review of Diagnosis and Management

Case Reports in Obstetrics and Gynecology, 2023
Introduction. Heterotopic pregnancy (HP) refers to the simultaneous presence of intrauterine pregnancy (IUP) and ectopic pregnancy, which is very rare but potentially life-threatening. The spontaneous incidence of HP in the general population is 1/30,000.
Somaia Elsayed, Nadine Farah, Mary Anglim   +2 more
doaj   +1 more source

The impact of revised diagnostic criteria on hospital trends in gestational diabetes mellitus rates in a high income country

BMC Health Services Research, 2020
Objective In 2010, national guidelines were published in Ireland recommending more sensitive criteria for the diagnosis of Gestational Diabetes Mellitus (GDM).
Léan E. McMahon, Eimer G. O’Malley, Ciara M. E. Reynolds, Michael J. Turner   +3 more
doaj   +1 more source

Single-Dose Nirsevimab for Prevention of RSV in Preterm Infants.

New England Journal of Medicine, 2020
BACKGROUND Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract infection in infants, and a need exists for prevention of RSV in healthy infants.
M. P. Griffin, Yuan Yuan, Therese Takas, J. Domachowske, S. Madhi, P. Manzoni, E. Simões, M. Esser, Anis A. Khan, F. Dubovsky, T. Villafana, J. DeVincenzo   +11 more
semanticscholar   +1 more source

Peptidome analysis of cerebrospinal fluid in neonates with hypoxic-ischemic brain damage

Molecular Brain, 2020
Hypoxic-ischemic brain injury (HIBD) causes neonatal death and serious neurological disability; however, there are currently no promising therapies for it excepting cooling.
Xuewen Hou, Zijun Yuan, Xuan Wang, Rui Cheng, Xiaoguang Zhou, Jie Qiu   +5 more
doaj   +1 more source