Results 91 to 100 of about 1,649,340 (344)

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

Advanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah, Remant KC, Amarnath Praphakar Rajendran, Saba Abbasi Dezfouli, Cezary Kucharski, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Olaf Heidenreich, Hasan Uludağ   +9 more
wiley   +1 more source

Top Cells for Silicon‐Based Tandem Photovoltaics

Advanced Materials, EarlyView.
The article provides a comprehensive review of Si‐based tandem solar cells, highlighting the advantages of silicon as a bottom cell and exploring top cell technologies including III–V compounds, perovskites, and emerging chalcogenide materials. It summarizes current challenges of these top cell materials and offers insights into future research ...
Mingrui He, Meng Zhang, Zhen Li, Xu Liu, Kaiwen Sun, Ziheng Liu, Xiaojing Hao   +6 more
wiley   +1 more source

Analysis of intestinal flora development in breast-fed and formula-fed infants by using molecular identification and detection methods.

Journal of Pediatric Gastroenterology and Nutrition - JPGN, 2000
BACKGROUND An obvious difference between breast-fed and formula-fed newborn infants is the development of the intestinal flora, considered to be of importance for protection against harmful micro-organisms and for the maturation of the intestinal immune ...
H. Harmsen, A. C. Wildeboer-veloo, G. C. Raangs, Arjen A. Wagendorp, N. Klijn, J. G. Bindels, Gjalt W. Welling   +6 more
semanticscholar   +1 more source

Retrospective Review on Reticular Materials: Facts and Figures Over the Last 30 Years

Advanced Materials, EarlyView.
To shape the future course of research in reticular materials, this work reflects on the progress over the past 30 years, complemented by input from the community of 228 active researchers through a global, crowdsourced survey: ranging from demographics, how it works, publish and interact, to highlights on both academic and industrial milestones, as ...
Aamod V. Desai, Stefano Canossa, Ekaterina A. Chernova, Simon M. Vornholt, Konstantin Stracke, Jack D. Evans, E. Eja Petersen, Stefan Wuttke, Romy Ettlinger   +8 more
wiley   +1 more source

Dermatologic presentations of hyper IgE syndrome in pediatric patients

Allergy, Asthma & Clinical Immunology
Background Hyper-IgE Syndrome, also known as Job’s syndrome, is a rare primary immunodeficiency disorder characterized by recurrent infections and elevated levels of immunoglobulin E.
Mohammad Mahjoubi, Ronak Rashedi, Noosha Samieefar, Fahimeh Abdollahimajd, Nima Rezaei   +4 more
doaj   +1 more source

THE NURSING INFANT [PDF]

Journal of the American Medical Association, 1915
The purpose of this paper is to offer some practical suggestions for the prevention and correction of those far too frequent nutritional disturbances of breast babies due to faulty feeding. During the first few months of infancy, there is probably more milk than at any other time during the nursing period, and the digestive system of the infant is ...
openaire   +3 more sources

State‐of‐the‐Art, Insights, and Perspectives for MOFs‐Nanocomposites and MOF‐Derived (Nano)Materials

Advanced Materials, EarlyView.
Different approaches to MOF‐NP composite formation, such as ship‐in‐a‐bottle, bottle‐around‐the‐ship and in situ one‐step synthesis, are used. Owing to synergistic effects, the advantageous features of the components of the composites are beneficially combined, and their individual drawbacks are mitigated.
Stefanos Mourdikoudis, Subhajit Dutta, Saqib Kamal, Sergio Gómez‐Graña, Isabel Pastoriza‐Santos, Stefan Wuttke, Lakshminarayana Polavarapu   +6 more
wiley   +1 more source

SYMPTOMATOLOGY IN INFANTS. [PDF]

JAMA: The Journal of the American Medical Association, 1883
By many persons, the study of disease in infants is regarded as peculiarly difficult, because of the absence of speech by which to indicate the presence and location of certain symptoms. The late Prof. C. D. Meigs, on the contrary, was wont to felicitate himself on this as an advantage. He would say, “An infant never tells a lie.” It cannot imitate the
openaire   +3 more sources

Nonintubated Surfactant Application vs Conventional Therapy in Extremely Preterm Infants: A Randomized Clinical Trial.

JAMA pediatrics, 2015
IMPORTANCE Treatment of respiratory distress syndrome in premature infants with continuous positive airway pressure (CPAP) preserves surfactant and keeps the lung open but is insufficient in severe surfactant deficiency.
A. Kribs, C. Roll, W. Göpel, C. Wieg, P. Groneck, R. Laux, N. Teig, T. Hoehn, W. Böhm, L. Welzing, M. Vochem, M. Hoppenz, C. Bührer, K. Mehler, H. Stützer, J. Franklin, Andreas Stöhr, E. Herting, B. Roth   +18 more
semanticscholar   +1 more source

Van Der Waals Hybrid Integration of 2D Semimetals for Broadband Photodetection

Advanced Materials, EarlyView.
Advanced broadband photodetector technologies are essential for military and civilian applications. 2D semimetals, with their gapless band structures, high mobility, and topological protection, offer great promise for broadband PDs. This study reviews the latest advancements in broadband PDs utilizing heterostructures that combine 2D semimetals with ...
Xue Li, Kunxuan Liu, Di Wu, Pei Lin, Zhifeng Shi, Xinjian Li, Longhui Zeng, Yang Chai, Shu Ping Lau, Yuen Hong Tsang   +9 more
wiley   +1 more source