Results 151 to 160 of about 405,700 (273)

Sperm‐Derived CircRNA‐1572 Regulates Embryogenesis and Zygotic Genome Activation by Targeting CCNB2 via Bta‐miR‐2478‐L‐2

open access: yesAdvanced Science, EarlyView.
Sperm‐derived circRNA‐1572 competitively binds to bta‐miR‐2478‐L‐2 through a “sponge” mechanism to regulate cyclin B2 (CCNB2) expression, thereby modulating the distribution of fibrous actin (F‐actin) in early pig embryos, ensuring proper chromosome segregation during mitosis, and facilitating normal embryo cleavage and zygotic genome activation.
Yanfang Wu   +10 more
wiley   +1 more source

Dedifferentiated endometrial adenocarcinoma with neuroendocrine differentiation and ballooning-cell features: Report of a rare entity with an unusual histology

open access: yesHuman Pathology: Case Reports, 2019
A 63-year-old Caucasian woman underwent total hysterectomy with bilateral salpingo-oophorectomy due to abnormal uterine bleeding. Gross examination of the hysterectomy specimen revealed a large polypoid mass filling the endometrial cavity.
Sara Makhdoum, MD   +4 more
doaj  

Exploiting sweet relief for preeclampsia by targeting autophagy-lysosomal machinery and proteinopathy

open access: yesExperimental and Molecular Medicine
The etiology of preeclampsia (PE), a severe complication of pregnancy with several clinical manifestations and a high incidence of maternal and fetal morbidity and mortality, remains unclear.
Zheping Huang   +11 more
doaj   +1 more source

Nuclear Translocation of S100A9 Triggers Senescence of Human Amnion Fibroblasts by De‐Repressing LINE1 Via Heterochromatin Erosion at Parturition

open access: yesAdvanced Science, EarlyView.
This study shows that the classical secretory protein S100 calcium‐binding protein A9 (S100A9) can translocate to the nucleus upon de‐phosphorylation at Thr 113 in human amnion fibroblasts at parturition, where S100A9 induces heterochromatin erosion through segregation of the heterochromatin maintenance protein, resulting inLong Interspersed Nuclear ...
Fan Zhang   +8 more
wiley   +1 more source

Thermo‐responsive topological metamorphosis in covalent‐and‐supramolecular polymer architectures

open access: yesAggregate, Volume 3, Issue 6, December 2022., 2022
We report a thermo‐responsive topological metamorphosis in covalent‐and‐supramolecular polymer (CSP) architectures wherein supramolecular graft polymer (SGP) transforms into supramolecular polymer network (SPN) based on collaborative dynamic covalent bond chemistry and host−guest chemistry.
Yongming Wang   +7 more
wiley   +1 more source

ProteoSeeker: A Feature‐Rich Metagenomic Analysis Tool for Accessible and Comprehensive Metagenomic Exploration

open access: yesAdvanced Science, EarlyView.
ProteoSeeker is a new metagenomic analysis tool that accelerates protein discovery. By automating key steps, it reduces computational complexity and enables comprehensive dataset analysis, performing protein identification, screening based on user‐defined protein families, and taxonomic analysis.
Georgios Filis   +6 more
wiley   +1 more source

Bio‐inspired functional coacervates

open access: yesAggregate, Volume 3, Issue 6, December 2022., 2022
Bio‐inspired functional coacervates have diverse functions. Natural and synthetic coacervates are a new class of materials that have great potential for various biomedical applications, including medical adhesives, drug delivery, and tissue engineering.
Shujun Chen, Qi Guo, Jing Yu
wiley   +1 more source

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