Results 261 to 270 of about 1,705,195 (343)

Deep Learning‐Assisted Rapid Bacterial Classification Based on Raman Spectroscopy of Bacteria Lysed by Acoustically Driven Fiber‐Tip Vibration

open access: yesAdvanced Science, EarlyView.
A novel acoustofluidic lysis technique based on a vibrating fiber‐tip is integrated with Raman spectroscopy and deep learning for rapid, label‐free bacterial classification. By exposing intracellular biomolecules, this method significantly enhances spectral resolution, enabling high‐accuracy classification with a 1D‐ResNet model.
Yukai Liu   +9 more
wiley   +1 more source

Medium‐Entropy Engineering Enhances Na⁺/Electron Transport in Na3Fe0.1Mn0.2Co0.2Ni0.3V1.2(PO4)2F3@CNTs Cathode for Sodium‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
This study proposes a medium‐entropy strategy to enhance sodium vanadium fluorophosphate cathodes. The designed Na3Fe0.1Mn0.2Co0.2Ni0.3V1.2(PO4)2F3@CNTs composite enhances structural stability and charge transport. Entropy‐induced distortion and carbon nanotubes (CNTs) synergistically improve Na⁺/electron kinetics. In situ XRD reveals a reversible dual‐
Ju Yang   +7 more
wiley   +1 more source

Nature‐Inspired Nanostructures from Multiple‐Species Biomembranes: Rational Engineering and Therapeutic Applications in Tumor‐Targeted Nanomedicine

open access: yesAdvanced Science, EarlyView.
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei   +10 more
wiley   +1 more source

SenExo‐cCCT2 Reprograms Senescence Response and Anti‐Tumor Immunity Following FOLFIRINOX Chemotherapy in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
This study demonstrates that SenExo‐cCCT2 enables targeted delivery of cCCT2 to pancreatic cancer cells, where it disrupts IPO13‐mediated nuclear translocation of UBC9, impairing SUMOylation‐dependent DNA damage repair and inducing senescence. Senescent tumor cells secrete CXCL10 to recruit CD8⁺ T‐cells while upregulating PD‐L1.
Shuncang Zhu   +18 more
wiley   +1 more source

Development of the "SMA NNE," a short neonatal neurological examination for newborns with spinal muscular atrophy. [PDF]

open access: yesEur J Pediatr
Mercuri E   +14 more
europepmc   +1 more source

Advancing Nitrate‐to‐Ammonia Electrocatalysis: Strategies in Catalyst Design, Electrolyte Engineering, and Performance Evaluation

open access: yesAdvanced Science, EarlyView.
This review highlights the latest advances in electrocatalytic nitrate reduction to ammonia, with a focus on catalyst design strategies, electrolyte engineering, and performance evaluation. Abstract The electrochemical reduction of nitrate for ammonia production not only offers a promising alternative to the traditional Haber–Bosch process, which ...
Juan Bai   +8 more
wiley   +1 more source

Hyperspectral Fluorescence Imaging with a New Polarity‐Ultrasensitive Fluorescent Probe

open access: yesAdvanced Science, EarlyView.
Based on the critical role of the π‐spacer in determining wavelength sensitivity to microenvironmental polarity, a new fluorescent probe, Lipi‐PS is rationally developed, which exhibits the highest polarity‐sensitivity so far. Its integration with hyperspectral fluorescence imaging enables multiscale polarity mapping across cells, tissues, and ...
Ri Zhou   +7 more
wiley   +1 more source

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