Results 311 to 320 of about 2,486,249 (388)

Targeting Hyperglycemic Bone Pre‐Metastatic Niche for Breast Cancer Bone Metastasis Therapy

Advanced Science, EarlyView.
This study reveals that breast cancer creates a hyperglycemic pre‐metastatic niche in bone prior to colonization and amplifies glucose metabolism post‐metastasis. To target this mechanism, a biomimetic enzyme‐engineered nanoplatform that disrupts tumor glycolytic pathways, proposing a therapeutic strategy to inhibit breast cancer bone metastasis by ...
Jianxin Ye, Peng Hu, Rui Zhang, Lei Zhou, Zonghua Luo, Yanan Chen, Shengzhe Ruan, Mengyi Zhu, Huaze Ding, Yike Qian, Yan Xing, Tong Meng, Changping Wang, Dianwen Song   +13 more
wiley   +1 more source

Corrigendum to effect of human milk-based fortification in extremely preterm infants fed exclusively with breast milk: a randomised controlled trial. [PDF]

EClinicalMedicine
Jensen GB, Domellöf M, Ahlsson F, Elfvin A, Navér L, Abrahamsson T.   +5 more
europepmc   +1 more source

Fullerene C70‐Encapsulated Tetrathiafulvalene‐Co Porphyrin Covalent Organic Framework: Driving Multistep Charge Transfer to Boost CO2 Photoreduction

Advanced Science, EarlyView.
The encapsulation of C70 into COF has improved the efficiency of photocatalytic CO2 reduction significantly. The introduction of C70 drives multistep charge transfer and forms a long‐lived charge‐separated state. It also thermodynamically lowers the energy barrier of the rate‐determining step.
Ying Jiang, Chong Wang, Tianyang Dong, Yupeng Song, Tao Wang, Haibing Che, Hua Sheng, Bo Wu, Chunru Wang   +8 more
wiley   +1 more source

Vitamin D status and its determinants among Chinese infants and toddlers in Hong Kong. [PDF]

Eur J Nutr
Tung KTS, So HK, Chen C, Tung JYL, Tsang HW, Wong RS, Leung SSF, Cheung CKM, Lee A, Yam JCS, Leung WC, Ip P.   +11 more
europepmc   +1 more source

The Long Noncoding RNA ΒFaar Promotes White Adipose Tissue Browning and Prevents Diet‐Induced Obesity

Advanced Science, EarlyView.
βFaar selectively targets and inhibits the GTPase activity of the RAB18 protein, thereby reducing LD volume. Conversely, βFaar promotes nuclear translocation of the transcription factor IRF4 in inguinal white adipose tissue (iWAT), facilitating the browning of white adipose tissue and attenuating body fat accumulation.
Yue Yang, Bin Huang, Baixue Sha, Danni Gao, Yimeng Qin, Ziyi Li, Xi Chen, Yinuo Jin, Yi Pan, Yanfeng Zhang, Yumeng Shen, Yu Liu, Liang Jin, Fangfang Zhang   +13 more
wiley   +1 more source

Effectiveness of nurses' training about mechanical ventilation weaning on neonatal outcomes. [PDF]

BMC Nurs
Alharbi MF, Marzouk SA, Alrashidi N, Abu-Alghayth MH, Mater EA, Ibrahim MA, Abdelmonem HH, Mohammed HA, Syan SA, Abdelrahem AS, Alshehri AD, Moursy SM, Almowafy AA, Ahmed FA.   +13 more
europepmc   +1 more source

Deciphering the Acetabular Labrum's Cellular Atlas: MDK Inhibition as a Novel Therapeutic Method for Developmental Dysplasia of the Hip

Advanced Science, EarlyView.
This study explores developmental dysplasia of the hip (DDH) by analyzing acetabular labrum abnormalities using single‐cell and spatial transcriptomics. Aberrant fibrocartilage stem cell proliferation is linked to DDH progression. Targeting the MK signaling pathway with a specific inhibitor effectively alleviates early DDH abnormalities, offering ...
Runze Yang, Huiling Liu, Minghao Ge, Dingyuan Zhang, Tianhao Xu, Lei Zhang, Yanlin Zhu, Shun Li, Jian Li, Xin Ma, Weili Fu   +10 more
wiley   +1 more source

Controlling Energy Flow in Perovskite Heterostructures Through Dimensionality and Phase Engineering

Advanced Science, EarlyView.
Advances in phase and dimensionality engineering offer powerful strategies to modulate energy flow in perovskite heterostructures. This Perspective highlights how structural control at the nanoscale enables precise tuning of energy transport processes for next‐generation optoelectronic applications.
Danila A. Tatarinov, Alexander Schleusener, Roman Krahne   +2 more
wiley   +1 more source

Controversies in Parenteral Protein Intake in Preterm Infants. [PDF]

Children (Basel)
Holla I, Alur P.
europepmc   +1 more source

Capturing the Electrical Activity of all Cortical Neurons: Are Solutions Within Reach?

Advanced Science, EarlyView.
Despite advancements in implantable electrode technology, challenges persist in scaling up these devices to record most of the neuronal activity across the cortex. This review explores the limitations of both rigid and flexible probes, including tissue damage and foreign body response, while also discussing emerging biohybrid strategies.
Attila Kaszás, Domokos Meszéna, Richárd Fiáth, Andrea Slézia, István Ulbert, Gergely Katona   +5 more
wiley   +1 more source