Results 51 to 60 of about 904,891 (304)

Neoadjuvant chemotherapy induces phenotypic mast cell changes in high grade serous ovarian cancer

Journal of Ovarian Research
Background High grade serous ovarian cancer (HGSOC) is the most lethal gynecologic malignancy in which patients have still yet to respond meaningfully to clinically available immunotherapies. Hence, novel immune targets are urgently needed. Our past work
Julia McAdams, Jasmine Ebott, Corinne Jansen, Chloe Kim, Daniela Maiz, Joyce Ou, Linda C. Hanley, Payton De La Cruz, Nicole E. James   +8 more
doaj   +1 more source

Pregnancy Complicated by Portal Hypertension Secondary to Biliary Atresia

Case Reports in Obstetrics and Gynecology, 2013
Biliary atresia is a rare idiopathic neonatal cholestatic disease characterized by the destruction of both the intra- and extrahepatic biliary ducts. As the disease is progressive all cases will develop portal fibrosis, cirrhosis, and portal hypertension
O. E. O'Sullivan, D. Crosby, B. Byrne, C. Regan   +3 more
doaj   +1 more source

How do breast cancer surgery scars impact survivorship? Findings from a nationwide survey in the United States

BMC Cancer, 2019
Background The surgical treatment of breast cancer has been associated with negative consequences for patients’ body image, sexual functioning, mental health, and social adjustment.
Jennifer Gass, Sunny Mitchell, Michael Hanna   +2 more
doaj   +1 more source

Protein Network Analysis of Whole Exome Sequencing of Severe Preeclampsia

Frontiers in Genetics, 2022
Preeclampsia is a hypertensive disorder of pregnancy, which complicates up to 15% of US deliveries. It is an idiopathic disorder associated with several different phenotypes.
Jessica Schuster, Jessica Schuster, George A. Tollefson, Valeria Zarate, Anthony Agudelo, Joan Stabila, Ashok Ragavendran, Ashok Ragavendran, James Padbury, James Padbury, James Padbury, Alper Uzun, Alper Uzun, Alper Uzun, Alper Uzun   +14 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Personal relatedness and attachment in infants of mothers with borderline personality disorder [PDF]

, 2005
The principal aim of this study was to assess personal relatedness and attachment patterns in 12-month-old infants of mothers with borderline personality disorder (BPD).
Crandell, L, Patrick, M, Hobson, RP, Garcia-Perez, R, Lee, A   +4 more
core  

Understanding the referential nature of looking: infants’ preference for object-directed gaze [PDF]

, 2008
In four experiments, we investigated whether 9-month-old infants are sensitive to the relationship between gaze direction and object location and whether this sensitivity depends on the presence of communicative cues like eye contact.
Johnson, Mark H., Atsushi Senju, Gergely Csibra, Senju, Atsushi, Mark H Johnson Birkbeck, Csibra, Gergely   +5 more
core   +1 more source

A Rare Nasopharyngeal Hemangioma Presenting as Recurrent Cyanotic Apnea in a Neonate: A Case Report and Literature Review

Case Reports in Medicine
Conclusion: Nasopharyngeal hemangiomas are rare and may present subtly in premature infants. Early bronchoscopy and imaging should be considered in cases of unexplained apnea or airway compromise. A multidisciplinary approach ensures timely diagnosis and
Pershia Davoodi Karsalari, Samin Mortaheb, Heliya Rafsanjani, Noosha Samieefar, Aslan Ahmadi, Parinaz Alizadeh   +5 more
doaj   +1 more source

MicroRNA 219-5p inhibits alveolarization by reducing platelet derived growth factor receptor-alpha

Respiratory Research, 2021
Background MicroRNA (miR) are small conserved RNA that regulate gene expression post-transcription. Previous genome-wide analysis studies in preterm infants indicate that pathways of miR 219-5p are important in infants with Bronchopulmonary Dysplasia ...
Amelia Freeman, Luhua Qiao, Nelida Olave, Gabriel Rezonzew, Samuel Gentle, Brian Halloran, Gloria S. Pryhuber, Amit Gaggar, Trent E. Tipple, Namasivayam Ambalavanan, Charitharth Vivek Lal   +10 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source