Results 221 to 230 of about 213,607 (256)

From first seizure to specific antiseizure medication in Dravet syndrome: Quantifying delays in the DS'coverED study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Dravet syndrome (DS) is a rare early‐onset developmental and epileptic encephalopathy with persistent delays between seizure onset and diagnosis. The DS'coverED study aimed to characterize current diagnostic timelines by examining each step and its duration, identifying residual barriers, and actionable solutions to optimize the ...
Loucas Christodoulou   +9 more
wiley   +1 more source

Shared molecular pathways in pediatric genetic epilepsies: Insights from a single‐center cohort of 80 patients

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Genetic epilepsies in childhood are highly heterogeneous, and approaches to identify shared biological mechanisms across distinct genetic etiologies remain limited. We aimed to investigate whether genes associated with pediatric genetic epilepsies in our heterogeneous cohort converge on common functional pathways.
Laura Hecher   +11 more
wiley   +1 more source

Respiratory pathogens in infants and young children with acute respiratory illness: a prospective cohort study, China, 2023-2024. [PDF]

open access: yesFront Public Health
Li Y   +18 more
europepmc   +1 more source

Genetic developmental and epileptic encephalopathies in adulthood: Gaps in evidence and care

open access: yesEpilepsia Open, EarlyView.
Abstract Developmental and epileptic encephalopathies (DEEs) are a heterogeneous group of the most severe epilepsies, characterized by seizure onset and neurodevelopmental delay in infancy or childhood, often with additional neurological and systemic comorbidities.
Alex M. Dudley   +5 more
wiley   +1 more source

Outcomes of Infants and Young Children With CNS Embryonal Tumors Using Pre-Irradiation Chemotherapy: A Decade Long Experience. [PDF]

open access: yesCancer Med
Prasad M   +13 more
europepmc   +1 more source

Identifying Affective Patterns in Patients With Eating Disorders: A Latent Profile Analysis

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Background Emotional difficulties are common among individuals with Eating Disorders (EDs). Following Panksepp's theoretical model, which conceptualises primary emotional systems as the evolutionary foundation of personality, this study aimed to identify distinct profiles of primary emotional systems within a clinical eating disorder (ED ...
Rachele Fasolato   +15 more
wiley   +1 more source

Prevalence of Medical and Psychiatric Comorbidities in Paediatric ARFID: A Meta‐Analysis

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Background Avoidant/Restrictive Food Intake Disorder (ARFID) is increasingly recognized as a complex paediatric feeding and eating disorder associated with significant medical and psychiatric burden. Methods This systematic review and meta‐analysis followed PRISMA guidelines and was prospectively registered in PROSPERO (CRD420251241490 ...
Nuria Blay Borch   +8 more
wiley   +1 more source

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