Results 91 to 100 of about 124,881 (307)

Computational modelling of emboli travel trajectories in cerebral arteries: Influence of microembolic particle size and density [PDF]

, 2014
This article has been made available through the Brunel Open Access Publishing Fund.Ischaemic stroke is responsible for up to 80 % of stroke cases. Prevention of the reoccurrence of ischaemic attack or stroke for patients who survived the first symptoms ...
A Adboix, B Murtagh, CA Basciano, D Bushi, Dario Fabbri, EML Chung, H Tanaka, JC Grotta, Michele Pinelli, MR Tullio Di, MS Pollanen, NJJ MacDougall, NU Weir, Quan Long, RL Macdonald, Saroj Das   +15 more
core   +2 more sources

Elevated Risk of Complications in Patients Receiving Dual Antithrombotic Therapy Undergoing Hepatectomy: A Single‐Center Audit of 749 Cases

Annals of Gastroenterological Surgery, EarlyView.
This single‐center retrospective study evaluated perioperative outcomes after hepatectomy in 749 patients, including 140 receiving ATT, using propensity score matching to compare ATT and non‐ATT cohorts. Under standardized perioperative management, ATT did not increase major bleeding, transfusion, or severe morbidity overall; however, within the ATT ...
Haruki Mori, Hiromitsu Maehira, Nobuhito Nitta, Takeru Maekawa, Toru Miyake, Sachiko Kaida, Masatsugu Kojima, Katsushi Takebayashi, Takeshi Sonoda, Masaji Tani   +9 more
wiley   +1 more source

Microrobotic Catheterization of the Ophthalmic Artery for Targeted Treatment of Retinoblastoma

Advanced Intelligent Systems, EarlyView.
A microrobotic platform is presented that allows teleoperated and autonomous navigation of flow‐driven magnetic microcatheters, MagFlow, into the ophthalmic artery for superselective intra‐arterial infusion of chemotherapy to treat retinoblastoma. Extensive benchtop validations with patient‐derived biomimetic phantoms under optical and fluoroscopic ...
Artur Banach, Mehdi Krichen, Julian Raub, Christina Stathopoulos, Bruno Bartolini, Mahmut Selman Sakar   +5 more
wiley   +1 more source

Real‐World Effectiveness and Safety of Ravulizumab in Patients With Paroxysmal Nocturnal Hemoglobinuria: Evidence From the International PNH Registry

American Journal of Hematology, EarlyView.
ABSTRACT Ravulizumab, a second‐generation complement component 5 inhibitor (C5i) derived from eculizumab, with improved pharmacokinetics, is the current standard‐of‐care treatment for patients with paroxysmal nocturnal hemoglobinuria (PNH), where available.
Alexander Röth, Christopher J. Patriquin, Jeff Szer, Louis Terriou, Ami S. Patel, Jesse Metzger, Philippe Gustovic, Jun‐ichi Nishimura, Robert A. Brodsky   +8 more
wiley   +1 more source

Glial and axonal body fluid biomarkers are related to infarct volume, severity, and outcome. [PDF]

, 2008
Body fluid biomarkers of central nervous system damage may help improve the prognostic and diagnostic accuracy in ischemic stroke. We studied 53 patients.
Michel, P, Petzold, A, Schluep, M, Stock, M   +3 more
core   +1 more source

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

Animal Models and Experimental Medicine, EarlyView.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao, Chunlan Zou, Junxian Li, Yang Yang, Yuanyuan Han, Tingyu Ke   +5 more
wiley   +1 more source

Intracranial pressure monitoring for malignant stroke: It is too soon to call it off

Brain Circulation, 2020
Malignant cerebral infarction (MCI) is a large middle cerebral artery infarction. MCI frequently results in increased intracranial pressure (ICP) because of its extent of the infarction.
Ho Jun Yun, Yuchuan Ding
doaj   +1 more source

Dislocation of a cerebral protection device component during carotid stenting: A case report of favorable outcome from conservative management after failure of retrieval [PDF]

, 2018
tINTRODUCTION: Cerebral-protection devices (CPDs) are a well-established system for reduction ofembolic risk in carotid artery angioplasty and stenting (CAS).
Avruscio, Giampiero, Kulyk, Caterina, Tocco-Tussardi, Ilaria, Vindigni, Vincenzo   +3 more
core   +2 more sources

DNase1 RS1053874 Polymorphism is Associated with Early Neurological Recovery through NET Modulation and with Long‐Term Survival in Ischemic Stroke: A Prospective Cohort Study

Annals of Neurology, EarlyView.
Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito, P. Calleja, L. Alzamora, A. Ruiz‐García, A. Martínez‐Salio, M. Muñoz‐García, F. Ostos, A. García‐Culebras, A. Moraga, M.A. Moro, I. Lizasoain   +10 more
wiley   +1 more source

Management of Malignant Middle Cerebral Artery Infarction [PDF]

European Medical Journal Neurology, 2015
Malignant middle cerebral artery (MCA) infarcts occur in a small subset of patients with ischaemic strokes and lead to high levels of disability and mortality.
Jennifer C. V. Gwyn, Tonny Veenith
doaj