Results 181 to 190 of about 125,957 (306)

Post‐marketing safety of CGRP monoclonal antibodies and gepants: A systematic review of spontaneous reporting system data

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective Calcitonin gene‐related peptide (CGRP) inhibitors, including monoclonal antibodies (mAbs) and small‐molecule antagonists (gepants), have transformed migraine treatment. Although clinical trials established their efficacy and initial safety, post‐marketing surveillance is essential for understanding their real‐world safety profile in ...
Martina Giacon, Salvatore Terrazzino
wiley   +1 more source

Serum nonmercaptalbumin to total albumin ratio and bilirubin predict ADL decline in older adults with type 2 diabetes

open access: yesJournal of Diabetes Investigation, EarlyView.
In a longitudinal cohort of older adults with type 2 diabetes, incident ADL disability was evaluated. Higher HNA%, lower serum bilirubin, and older age independently predicted the risk of disability. Their combined assessment may offer clinically useful tools for identifying individuals at elevated risk of functional deterioration.
Yukihiro Inoguchi   +10 more
wiley   +1 more source

Co‐pathologies and biological processes beyond amyloid‐beta and tau in people with Alzheimer's disease: Evidence from clinical cohort studies

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Alzheimer's disease (AD) is neuropathologically defined by amyloid‐beta (Aβ) plaques and tau neurofibrillary tangles. However, co‐pathologies and other pathobiological processes are involved in the pathogenesis of AD, contributing to neurodegeneration and clinical symptoms.
Daniel Ferreira   +9 more
wiley   +1 more source

Modified Anatomical Ablation Strategy for Mitral Isthmus

open access: yesPacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background Durable mitral isthmus (MI) block remains challenging in persistent atrial fibrillation (AF) ablation. Ethanol infusion into the vein of Marshall (EI‐VOM) enhances efficacy, but the minimal endocardial ablation extent post‐EI‐VOM is undefined.
Kui He   +7 more
wiley   +1 more source

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