Repression of the Glucocorticoid Receptor Aggravates Acute Ischemic Brain Injuries in Adult Mice. [PDF]
, 2018 Strokes are one of the leading causes of mortality and chronic morbidity in the world, yet with only limited successful interventions available at present.
Concepcion, Katherine R +8 more
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Arquivos de Neuro-Psiquiatria, 2023 Background Brain edema is the leading cause of death in patients with malignant middle cerebral artery (MCA) infarction. Midline shift (MLS) has been used as a monohemispheric brain edema marker in several studies; however, it does not precisely measure ...
Thiago Pereira Rodrigues +8 more
doaj +1 more source
Inhibition of the potassium channel Kv1.3 reduces infarction and inflammation in ischemic stroke. [PDF]
, 2018 ObjectiveInhibitors of the voltage-gated K+ channel Kv1.3 are currently in development as immunomodulators for the treatment of autoimmune diseases. As Kv1.3 is also expressed on microglia and has been shown to be specifically up-regulated on "M1-like ...
Azam +49 more
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Malignant middle cerebral artery infarction [PDF]
BMJ Case Reports, 2017 A 55-year-old man with hypertension was referred from a rural hospital. Two days before, he had developed a cardioembolic ischaemic stroke, which resulted in left-sided hemiparesis and hemianaesthesia. On the day of referral, he developed repeated vomiting and severe headache, followed by progressive obtundation and coma. There was papilloedema.
openaire +2 more sources
Which one to do first?: a case report of simultaneous acute ischemic stroke and myocardial infarction [PDF]
Journal of Neurocritical Care, 2021 Background Although there are common risk factors for acute ischemic stroke and myocardial infarction, simultaneous onset of both diseases is uncommon. Here, we present a case of acute cerebral infarction with concurrent fatal myocardial infarction. Case
Kijeong Lee +3 more
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Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat [PDF]
, 2004 Results from several studies indicate that cyclooxygenase-2 (COX-2) is involved ischemic brain injury. The purpose of this study was to evaluate the neuroprotective effects of the selective COX-2 inhibitor nimesulide on cerebral infarction and ...
Candelario-Jalil, Eduardo +4 more
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International Journal of Immunopathology and Pharmacology, 2018 Occlusion of arteries in the brain is a common cause of cerebral infarction which induces inflammatory response and oxidative stress resulting in neuronal apoptosis and disruption of neurological function.
Lemen Pan, Shuxia Qian
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Nucleosomes in serum of patients with early cerebral stroke [PDF]
, 2006 Background: Nucleosomes are cell death products that are elevated in serum of patients with diseases that are associated with massive cell destruction.
Adams +22 more
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Early recurrent ischemic stroke complicating intravenous thrombolysis for stroke: incidence and association with atrial fibrillation [PDF]
, 2010 <p><b>Background and Purpose:</b> Mechanisms of early neurologic deterioration after treatment with intravenous, recombinant, tissue-type plasminogen activator (IV rt-PA) include symptomatic intracerebral hemorrhage (SICH) and early ...
Awadh, M. +5 more
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IgG4-related small-sized occlusive vasculitis in Mikulicz's disease
Journal of Vascular Surgery Cases and Innovative Techniques, 2019 Mikulicz's disease is one of the IgG4-related diseases (IgG4-RDs) that involves the cardiovascular system; however, small-sized vasculitis is rare in IgG4-related diseases.
Kuniyasu Ikeoka, MD, PhD +6 more
doaj +1 more source