Results 221 to 230 of about 125,957 (306)

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò   +18 more
wiley   +1 more source

Ultrafast Blood T1 Measurement Using Golden Angle Rotated Spiral k‐t Sparse Parallel Imaging (GASSP): Evaluations in Both Pre‐ and Post‐Contrast Conditions

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 6, Page 3351-3359, June 2026.
ABSTRACT Purpose Blood T1 is a key parameter for hemodynamic quantification in both non‐contrast‐ and contrast‐enhanced imaging. Individual vessel T1 has been measured using a modified Look–Locker scheme with multi‐shot EPI or FLASH in high spatial resolution, requiring ∼1 min.
Zechen Xu, Feng Xu, Qin Qin, Dan Zhu
wiley   +1 more source

Combination Versus Monotherapy in Acute Anti‐LGI1 Encephalitis: A Real‐World Dose Optimization Analysis

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
Combined IVIg and 500 mg/day IVMP achieve superior efficacy over monotherapies in anti‐LGI1 encephalitis, with optimal safety. Higher‐dose IVMP (1000 mg) accelerates response but increases adverse events, particularly in diabetic patients. Cognitive deficits persist post‐treatment, necessitating long‐term management.
Yao Tan   +6 more
wiley   +1 more source

Real‐World Effectiveness and Safety of Ravulizumab in Patients With Paroxysmal Nocturnal Hemoglobinuria: Evidence From the International PNH Registry

open access: yesAmerican Journal of Hematology, Volume 101, Issue 5, Page 939-948, May 2026.
ABSTRACT Ravulizumab, a second‐generation complement component 5 inhibitor (C5i) derived from eculizumab, with improved pharmacokinetics, is the current standard‐of‐care treatment for patients with paroxysmal nocturnal hemoglobinuria (PNH), where available.
Alexander Röth   +8 more
wiley   +1 more source

Postoperative symptomatic vasospasm in pituitary surgery: case series and systematic review - a matter of blood? [PDF]

open access: yesNeurosurg Rev
Sannwald LW   +9 more
europepmc   +1 more source

DNase1 RS1053874 Polymorphism is Associated with Early Neurological Recovery through NET Modulation and with Long‐Term Survival in Ischemic Stroke: A Prospective Cohort Study

open access: yesAnnals of Neurology, Volume 99, Issue 5, Page 1210-1223, May 2026.
Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito   +10 more
wiley   +1 more source

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