Results 91 to 100 of about 785,029 (297)

Microneedles From Shape‐Preserving Crosslinked Poly(Vinyl Alcohol) Hydrogels: Minimising Interference in Transdermal Proteomics

open access: yesAdvanced Materials Technologies, EarlyView.
Hydrogel‐forming microneedle patches are developed using shape‐preserving PVA‐PVP hydrogels, with and without chitosan, for minimally invasive transdermal protein biomarker sampling. The optimised patches enable efficient interstitial fluid uptake and proteomic analysis, while minimising interference.
Achmad Himawan   +12 more
wiley   +1 more source

Functional outcome predictors and recanalization in cerebral venous thrombosis: A single-center cross-sectional study

open access: yesTurkish Journal of Emergency Medicine
OBJECTIVES Cerebral venous thrombosis (CVT) is a rare type of stroke. Functional outcome (FOC) in CVT can be affected by different factors, and recanalization is an important determinant.
Rizwana Shahid, Azra Zafar
doaj   +1 more source

Precision Diagnostics in Sports‐Related Traumatic Brain Injury: Pathophysiology, Biomarker Development and Emerging Technologies

open access: yesAdvanced Sensor Research, EarlyView.
Sports‐related traumatic brain injuries (TBIs) remain underdiagnosed, within amateur athletic cohorts. This review critically synthesises recent advancements in AI‐assisted neuroimaging, blood‐based biomarker profiling, wearable biosensing platforms for early detection, injury stratification, and longitudinal surveillance of TBIs.
Daniel Nicol   +3 more
wiley   +1 more source

Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity

open access: yesAdvanced Science, EarlyView.
This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong   +16 more
wiley   +1 more source

Lacunar Infarct

open access: yesClinical and Experimental Hypertension, 2006
The term lacuna, or cerebral infarct, refers to a well-defined, subcortical ischemic lesion at the level of a single perforating artery, determined by primary disease of the latter. The radiological image is that of a small, deep infarct. Arteries undergoing these alterations are deep or perforating arteries with a diameter ranging between 100 and 400 ...
openaire   +2 more sources

Injectable BMSC‐Based Extracellular Matrix‐Mimicking Microtissue for Myocardial Infarction Repair

open access: yesAdvanced Science, EarlyView.
A novel injectable biomimetic extracellular matrix scaffold (JLSV) is designed for enhanced delivery of bone marrow‐derived mesenchymal stem cells (BMSCs). By utilizing janus basic nanotubes, laminin, stromal‐derived factor‐1 alpha, and vascular endothelial growth factor, this innovative JLSV–BMSC microtissue shows promise in myocardial infarction ...
Lina Yao   +7 more
wiley   +1 more source

The Ballistocardiogram in Myocardial Infarction: A Study of One Hundred Cases [PDF]

open access: bronze, 1952
Marvin Moser   +4 more
openalex   +1 more source

Glycolytic Enzyme HK2 Phosphorylates nSMase1 to Promote Astrocytic Exosomes Biogenesis Contributing to Acute Ischemic Stroke Injury

open access: yesAdvanced Science, EarlyView.
This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen   +12 more
wiley   +1 more source

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