Results 191 to 200 of about 1,298,858 (339)

SIRT6 Lysine‐Demyristoylates ATF2 to Ameliorate Vascular Injury via PRKCD/VE‐Cadherin Pathway Regulating Vascular Endothelial Barrier

open access: yesAdvanced Science, EarlyView.
A novel modified SIRT6 variant (dSIRT6) H133Y‐mediated enrichment technique unmasks 15 new human lysine‐myristoylated proteins. Notably, Sirtuin 6 (SIRT6) demyristoylation of activating transcription factor 2 (ATF2) at K296 orchestrates its nucleoplasmic translocation.
Runyang Feng   +40 more
wiley   +1 more source

Infarcted Tongue [PDF]

open access: yesJournal of the Royal Society of Medicine, 1984
M, Strome, J H, Kelly
openaire   +2 more sources

Nanoparticle Drug Delivery Systems for Atherosclerosis: Precision Targeting, Inflammatory Modulation, and Plaque Stabilization

open access: yesAdvanced Science, EarlyView.
This review first summarizes the complex pathogenesis of atherosclerosis and outlines the limitations of conventional therapies. It then explores innovative nanoparticle drug delivery system (NDDS) developments, detailing their precision targeting strategies, responsiveness to plaque‐specific stimuli, modulation of key pathological processes, and ...
Yunqi Zhang   +13 more
wiley   +1 more source

Recent Myocardial Infarction [PDF]

open access: bronze, 1953
Edgar Allen   +3 more
openalex   +1 more source

Adaptive Antioxidant Nanomedicines Inhibit Ferroptosis in Renal Tubular Epithelial Cells to Alleviate Diabetic Kidney Disease

open access: yesAdvanced Science, EarlyView.
In this study, an adaptive antioxidant nanodrug (AAN) is developed through the self‐polymerization of L‐selenocysteine. The AAN exhibits dual functionalities: antioxidant activity (scavenging reactive oxygen species) and mitochondrial targeting. Moreover, the released selenium (Se) participates in the synthesis of glutathione peroxidase 4 (GPX4), which
Zerun Liu   +15 more
wiley   +1 more source

Self-gated late gadolinium enhancement at 7T to image rats with reperfused acute myocardial infarction [PDF]

open access: yes, 2018
Chen, Wei   +8 more
core   +2 more sources

A Novel Transfer Learning‐Based Hybrid EEG‐fNIRS Brain‐Computer Interface for Intracerebral Hemorrhage Rehabilitation

open access: yesAdvanced Science, EarlyView.
The study has developed the first clinically validated hybrid EEG‐fNIRS brain‐computer interface fusion framework that systematically overcomes cross‐subject generalization barriers through a novel Wasserstein metric‐driven neural template selection mechanism.
Danyang Chen   +18 more
wiley   +1 more source

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