Results 271 to 280 of about 1,818,543 (386)

Neuroprotective Nanoplatform Integrating Antioxidant MXene Nanozymes and Ferroptosis Inhibitors for Targeted Therapy of Cerebral Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Cerebral ischemia‐reperfusion injury (CIRI) is a key pathological process limiting the efficacy of stroke therapy. This study has developed an innovative, multifunctional, brain‐targeted nanoplatform (RFP) containing MXene nanoenzymes and ferroptosis inhibitors.
Lu Wang   +9 more
wiley   +1 more source

Lower motor neuron facial palsy unmasking a rare brainstem stroke: a case report of medial Pontomedullary junction infarction. [PDF]

open access: yesOxf Med Case Reports
Frhood AM   +8 more
europepmc   +1 more source

Acute Myocardial Infarction in Women: A Scientific Statement From the American Heart Association

open access: yesCirculation, 2016
L. Mehta   +10 more
semanticscholar   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

open access: yesAdvanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang   +7 more
wiley   +1 more source

Reinstating Niche Failure in Diabetic Cranial Defects via Chronotaxic Signal‐Amplifying Fluidic Biomimetic Hydrogel

open access: yesAdvanced Science, EarlyView.
An in situ moldable GelSSO/PDA@SDF hydrogel functions as a chronotaxic signal‐amplifying biomimetic niche to restore regenerative failure in diabetic cranial defects. By sequentially releasing SDF‐1α‐loaded PDA nanoparticles and osteoinductive oligodeoxynucleotides, it orchestrates immunomodulation, progenitor recruitment, angiogenesis, and ...
Yingji Mao   +5 more
wiley   +1 more source

Mitochondrial Adaptation to Mechanical Stress in Cardiac Ageing and Disease

open access: yesAdvanced Science, EarlyView.
Mechanical forces shape the heart's energy factories. This review explores how mitochondria in cardiac cells sense and respond to biomechanical stress, altering their structure, positioning, and metabolism. By linking mechanical cues to mitochondrial adaptation, the article highlights pathways driving heart disease and points to new strategies for ...
Aishwarya Prakash, Thomas Iskratsch
wiley   +1 more source

Long-term effectiveness of ACE inhibitors or angiotensin receptor blockers in myocardial infarction with preserved left ventricular ejection fraction. [PDF]

open access: yesEur Heart J Cardiovasc Pharmacother
Humphreys ABC   +9 more
europepmc   +1 more source

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