Results 271 to 280 of about 1,313,166 (340)

Pharmacokinetics of betamethasone in pre‐eclampsia: An in vivo and ex vivo study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims To enhance understanding of betamethasone and its metabolites' pharmacokinetics in pregnancy, specifically early‐onset pre‐eclampsia, through a population pharmacokinetic model. Additionally, to investigate the placental metabolism and transfer of betamethasone and its main metabolites.
Sam Schoenmakers   +15 more
wiley   +1 more source

The use of international classification of diseases codes to identify hospital admissions linked with adverse drug events: Validation study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Several methods exist to identify hospital admissions related to adverse drug events (ADEs). Clinical adjudication by healthcare professionals is the gold standard but is labour‐intensive. Spontaneous reporting and routinely collected healthcare data using a set of International Classification of Diseases (ICD) codes often underestimate the ...
Zuzana Juhásová   +2 more
wiley   +1 more source

Aminated graphene nanosheet stimulates the maturation of hiPSCs‐derived cardiomyocytes in vitro and enhances their survival in vivo

open access: yesBMEMat, EarlyView.
Aminated graphene (G‐NH2) niche matrix plays a pivotal role in precisely manipulating cardiac differentiation and maturation of hiPSCs. The molecular mechanism underlying cardiomyocyte maturation is closely linked to the PDGF‐β signaling pathway. Cardiomyocytes derived from the G‐NH2 matrix exhibit enhanced activity and functionality in vivo.
Yin Xu   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy