Results 121 to 130 of about 3,746,616 (308)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Recommendations for Prevention and Control of Infections in Neonatal Intensive Care Unit Patients: Staphylococcus aureus [2020] [PDF]

Recommendations for the Prevention and Control of Staphylococcus aureus in Neonatal Intensive Care Unit Patients provides new, evidence-based recommendations specific to the prevention and control of Staphylococcus aureus (S.

core  

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Role of the nurses on antimicrobial stewardship team (AST) in single university hospital in Japan

Journal of Infection and Public Health, 2020
S. Miki, Y. Yuka, M. Yuki, K. Ai, K. Shunji, S. Arufumi, A. Nobuhiro, K. Yusuke, M. Hiroshige   +8 more
doaj   +1 more source

Building a coronavirus disease 2019 healthcare registry in an evolving pandemic

Scientific Reports
COVID-19 emerged in Wuhan, China in December 2019 and was declared a pandemic on March 11, 2020. As there were many unknowns about COVID-19, an immediate priority early in the pandemic was to collect high-quality data to understand disease ...
Indumathi Venkatachalam, Edwin Philip Conceicao, Jean Xiang Ying Sim, Shalvi Arora, Yue Yang, Jin Yee Shoon, Yingqi Xu, Marcus Eng Hock Ong, Sze Ling Chan   +8 more
doaj   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Guidance on public reporting of healthcare-associated infections: recommendations of the Healthcare Infection Control Practices Advisory Committee [PDF]

"Embargoed until Monday, February 28, 2005 at 12:30 pm."Since 2002, 4 states have enacted legislation that requires health care organizations to publicly disclose health care-associated infection (HAI) rates.
Hospital Infection Control Practices Advisory Committee (U.S.)
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Bodily waste management and related hygiene practices in nursing homes of Vaud: findings from a multicentre cross-sectional survey as a basis for targeted interventions

Antimicrobial Resistance and Infection Control
Introduction Bodily waste management is a critical yet frequently neglected domain of infection prevention and control. We conducted a survey to examine various aspects of bodily waste management and related hygiene practices in nursing homes (NH) based ...
Emmanouil Glampedakis, Marie-Catherine Snoussi, Béatrix Sobgoui, Firmino Battistella, Patricia Cuiña Iglesias, Coralie Riccio, Laetitia Qalla-Widmer, Alessandro Cassini, Marie Immaculée Nahimana Tessemo   +8 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Orthopaedic device-related infection: current and future interventions for improved prevention and treatment

, 2016
Orthopaedic and trauma device-related infection (ODRI) remains one of the major complications in modern trauma and orthopaedic surgery.Despite best practice in medical and surgical management, neither prophylaxis nor treatment of ODRI is effective in all
Riool, Martijn, Kates, Stephen L., Metsemakers, Willem-Jan, Schwarz, Edward M., Coenye, Tom, Khana, Nina, Richards, R. Geoff, Zaat, Sebastiaan A. J., Moriarty, T. Fintan, Kuehl, Richard, Morgenstern, Mario   +10 more
core   +1 more source