Results 91 to 100 of about 4,560,828 (303)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Инфекция и иммунитет, 2016 Introduction of flow cytometry caused an increase in the investigation of liquor lymphocyte pool phenotype in the case of different brain disorders, including viral and bacterial meningitis, however this type of research in children has been relatively ...
L. A. Alekseeva +6 more
doaj +1 more source
Antimicrobial use in European acute care hospitals: results from the second point prevalence survey (PPS) of healthcare-associated infections and antimicrobial use, 2016 to 2017 [PDF]
, 2018 Antimicrobial agents used to treat infections are life-saving. Overuse may result in more frequent adverse effects and emergence of multidrug-resistant microorganisms.
Aghdassi, S. +69 more
core +7 more sources
Streptococcal infections [PDF]
Jornal de Pediatria, 1999 OBJECTIVES: To review the main diseases caused by the different strains of streptococcus, and to discuss the practical aspects of clinical diagnosis and the range of therapeutic treatments. METHODOLOGY: A review of the literature and a selection of the most meaningful themes for the pediatricians.
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
THE ROLE AND PLACE OF LOGISTIC REGRESSION AND ROC ANALYSIS IN SOLVING MEDICAL DIAGNOSTIC TASK
Журнал инфектологии, 2016 Diagnostics, equally with prevention and treatment, is a basis of medical science and practice. For its history the medicine has accumulated a great variety of diagnostic methods for different diseases and pathologic conditions.
S. G. Grigoryev +2 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Changes in malaria epidemiology in Germany, 2001–2016: a time series analysis
Malaria Journal, 2018 Background German surveillance data showed a sharp rise of malaria cases in 2014 and 2015 due to the increased arrival of refugees from malaria endemic countries.
Sabine Vygen-Bonnet, Klaus Stark
doaj +1 more source
Fungal infections after liver transplantation [PDF]
, 1988 The risk factors for development of invasive fungal infections after liver transplantation were (1) longer duration of treatment with nonprophylactic IV antibiotics, (2) longer cumulative surgical time and a higher number of laparotomies, (3) an ...
Dummer, JS +6 more
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