Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network : Neisseria meningitidis, 2018 [PDF]
Citation:Centers for Disease Control and Prevention. 2018. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Neisseria meningitidis, 2018.
core
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Canadian Public Health Laboratory Network Statement on Point-of-Care Serology Testing in COVID-19
Canada Communicable Disease Report, 2020 Respiratory Virus Infections Working Group
doaj +1 more source
Characterization of tularemia foci in the Republic of Kazakhstan from 2000 to 2020
Frontiers in EpidemiologyThe wide distribution of tularemia in the territory of Kazakhstan is associated with landscape and geographical characteristics. This is explained by a combination of natural factors: the presence of certain types of rodents—reservoirs and sources ...
U. Izbanova +8 more
doaj +1 more source
Active Bacterial Core Surveillance (ABCs) report : Emerging Infections Program Network : Neisseria meningitidis, 2019 [PDF]
Citation: Centers for Disease Control and Prevention. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Neisseria meningitidis, 2019. www.cdc.gov/abcs/downloads/NMEN_Surveillance_Report_2019.pdfPublication date from document
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Infection Prevention in PracticeSUMMARY: Carbapenemase-producing organisms (CPOs) are an increasing global public health threat for which there are limited effective and affordable therapeutic options. The rise in the incidence of CPO infections and colonisations recorded across the UK
Akaninyene Otu +12 more
doaj +1 more source
Active Bacterial Core Surveillance (ABCs) Report Emerging Infections Program Network Group B Streptococcus, 2020 [PDF]
Dataset version: Jul 2022; Final run: Sep 20, 2022Citation: Centers for Disease Control and Prevention. 2020. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Group B Streptococcus, 2020.
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source