Results 41 to 50 of about 2,858,116 (267)

Immunoglobulin Depletion and Recovery Following Blinatumomab in Infants With KMT2A‐Rearranged ALL

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Adding blinatumomab to standard chemotherapy for infants with KMT2A‐rearranged acute B‐cell lymphoblastic leukemia (KMT2A‐r B‐ALL) improves outcomes. Although blinatumomab impairs immunoglobulin G (lgG) production, increasing infection susceptibility, IgG recovery remains poorly understood.
Miguel Vieira Martins   +14 more
wiley   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean   +7 more
wiley   +1 more source

Antibodies Recognizing Yersinia enterocolitica Lipopolysaccharides of Various Chemotypes in Synovial Fluids From Patients With Juvenile Idiopathic Arthritis

open access: yesJournal of Immunology Research, 2022
Yersinia enterocolitica O:3 (YeO3) is considered to be associated with reactive arthritis (ReA), and its lipopolysaccharide (LPS) has been detected in synovial fluids from patients. Interestingly, YeO3 wild-type LPS was processed by host cells, resulting
Katarzyna Kasperkiewicz   +6 more
doaj   +1 more source

Development and Implementation of a Disease‐Targeted Storybook as a Clinical Tool for Children With Acute Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Although significant progress has been made in childhood leukemia survival, healthcare providers, and caregivers often face challenges in explaining this disease to patients. Disease‐targeted storybooks have been proposed as a tool to facilitate the understanding of diagnoses and treatment.
Nutvipha Ummartyotin   +6 more
wiley   +1 more source

CONTEMPORARY POSSIBILITIES OF EXTRA NONSPECIFIC PROPHYLAXIS OF TICK BORN ENCEPHALITIS IN CHILDREN

open access: yesПедиатрическая фармакология, 2007
The present article contains new access to encephalitis. Results of different tactics of extra nonspecific prophylaxis of tick born used in 403 patients, who applied to hospitals for help after tick bite.
N.V. Skripchenko   +9 more
doaj   +2 more sources

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier   +11 more
wiley   +1 more source

CYCLOFERON USE IN COMPLEX THERAPY OF CHILDREN WITH SALMONELLOSIS AND YERSINIOSIS INFECTION

open access: yesАнтибиотики и Химиотерапия, 2020
The efficacy of cycloferon in complex therapy of salmonellosis and yersiniosis in children (n=220) was investigated under clinical and laboratory conditious.
A. S. Kvetnaya   +3 more
doaj  

Pathogenesis of formation of frequent respiratory infections in children with Epstein-Barr virus and cytomegalovirus infection

open access: yesЖурнал инфектологии, 2014
The goal was to clarify the pathogenesis of the formation of frequent respiratory infections in children with Epstein-Barr virus and cytomegalovirus infection on the basis of studying the microbial landscape of anti-infective and mucous membranes of the ...
I. V. Babachenko   +3 more
doaj   +1 more source

Comparative in silico genome analysis of Clostridium perfringens unravels stable phylogroups with different genome characteristics and pathogenic potential

open access: yesScientific Reports, 2021
Clostridium perfringens causes a plethora of devastating infections, with toxin production being the underlying mechanism of pathogenicity in various hosts. Genomic analyses of 206 public-available C.
Mostafa Y. Abdel-Glil   +6 more
doaj   +1 more source

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