Results 301 to 310 of about 3,511,887 (378)

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

Correction to: The Clinical Picture Caused by <i>Fasciola gigantica</i>: Analysis of 3250 Patients Along the 1995-2019 Countrywide Spread in Vietnam. [PDF]

Open Forum Infect Dis
europepmc   +1 more source

Vaccines for Global Health: Progress and Challenges. [PDF]

J Infect Dis
Knisely JM, Erbelding E.
europepmc   +1 more source

Impact of the COVID-19 pandemic on surgical site infections: a multi-center study evaluating incidence, pathogen distribution, and antimicrobial resistance patterns. [PDF]

Antimicrob Resist Infect Control
Keske Ş, Altunok ES, Azak E, Gülten E, Gülen TA, Hatipoğlu ÇA, Asan A, Korkmaz D, Kaçmaz B, Kızmaz Y, Batırel A, Akgül F, Yapar D, Karakoç ZÇ, Özel AS, Yalçın TY, Özer D, Korkmaz ÖE, Şahin A, Karaşın MF, Turunç T, Aydın M, Demirtürk N, Azap A, Ergönül Ö.   +24 more
europepmc   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Incorporating Ethics in Clinical Guidelines in Infectious Diseases: A Scoping Review.

JAMA Netw Open
Yahav D, Nasim A, Shirin N, Armellini M, Zanchi C, Tunali V, Mirandola M, Barac A, Scudeller L, Nagavci B, Paño-Pardo JR, Rodríguez-Baño J, Jamrozik E, Akova M, Righi E.   +14 more
europepmc   +1 more source

Early Diagnosis and Successful Treatment of Infectious Aortitis in a Hemodialysis Patient Through Physical Examination and Imaging. [PDF]

Cureus
Higashide R, Ohara Y, Kodama T, Yasuhara R, Toda T.   +4 more
europepmc   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source