Results 101 to 110 of about 2,894,136 (354)

GPR37 Activation Alleviates Bone Cancer Pain via the Inhibition of Osteoclastogenesis and Neuronal Hyperexcitability

open access: yesAdvanced Science, EarlyView.
GPR37 activation alleviates bone cancer pain via peripheral and neuronal mechanisms. NPD1 or ARU targeting GPR37 in macrophages promotes IL‐10 release through β‐arrestin 2 recruitment, thereby inhibiting cancer‐induced osteoclastogenesis. Additionally, GPR37 activation in the DRG and SDH reduces the No. of action potentials and the frequency of sEPSCs,
Kaiyuan Wang   +10 more
wiley   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

FERROPTOSIS IN CD4+ AND CD8+ T-CELLS IN THE SETTINGS OF HIV INFECTION

open access: yesProblems of Infectious and Parasitic Diseases
Introduction: Elevation of intracellular iron concentration triggers ferroptosis. Understanding the regulation and pathophysiological mechanisms of this process in HIV infection may contribute to antiretroviral therapy (cART) monitoring.
Radoslava Emilova   +8 more
doaj   +1 more source

Multiplex PCR Assay for Identifi cation and Differentiation of Campylobacter jejuni and Campylobacter coli Isolates

open access: yesFolia Medica, 2016
Introduction: Campylobacter spp. are important causative agents of gastrointestinal infections in humans. The most frequently isolated strains of this bacterial genus are Campylobacter jejuni and Campylobacter coli. To date, genetic methods for bacterial
Pavlova Maria R.   +9 more
doaj   +1 more source

Major animal health problems of market oriented livestock development in Alamata woreda [PDF]

open access: yes, 2010
An attempt was made to study major health problems of livestock in Alamata Woreda, northern Ethiopia, from December 2006 to April 2007. Questionnaire survey was carried out on 100 livestock owners to collect information on the livestock production system
Tekle, Y.
core  

Risk ranking of foodborne parasites : state of the art [PDF]

open access: yes, 2017
A
Bouwknegt, Martijn   +10 more
core   +2 more sources

Sheep Diseases [PDF]

open access: yes, 1944
In considering the field of sheep diseases we can roughly divide them into three general groups: (1) infectious, (2) non-infectious, and (3) parasitic. In Iowa most of our conditions are concerned with problems of parasitism and/or nutrition.
Beardmore, H. F.
core   +2 more sources

A conservative treatment for eosinophilic cystitis

open access: yesIJU Case Reports, Volume 6, Issue 1, Page 8-12, January 2023., 2023
Introduction Eosinophilic cystitis is a rare condition which causes common symptoms and may mimic other conditions. Eosinophilic cystitis has several causes such as hypereosinophilic syndrome, inflammatory diseases, neoplasia, parasites or fungal infection, IgE‐related diseases, Drug Reaction and Eosinophilia and Systemic Symptoms (DRESS) syndrome, or ...
Franco Alchiede Simonato   +6 more
wiley   +1 more source

SALIVARY SPECIFIC IgE TO D1 AND G6 IN PATIENTS WITH RHINITIS WITH OR WITHOUT S. AUREUS COLONIZATION

open access: yesProblems of Infectious and Parasitic Diseases
Globally, allergic rhinitis impacts roughly 25% of children and 40% of adults. Immunoglobulin E (IgE) plays a crucial part in allergic inflammation, with two sources: spontaneously produced IgE, and IgE stemming from reactions to environmental allergens.
Diana Hristova   +6 more
doaj   +1 more source

Parasites and Infectious Diseases: Discovery by Serendipity and Otherwise [PDF]

open access: yesEmerging Infectious Diseases, 2008
The author of this book retells several of the famous stories of discovery in the field of vector-borne and parasitic diseases through the eyes of some of the most prominent researchers working in this field today. But Esch does not stop there—he goes on to connect these early stories with more recent watershed contributions as recounted through a ...
openaire   +3 more sources

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